Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 20/20 | 1.00 |
| ▸ | CHUK | O15111 | 5/20 | 0.52 |
| ▸ | BTK | Q06187 | 2/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL618943 | 1.00 | IKBKB (1.00) | IKBKBCHUKBTKCSF1RAURKA | |
| SCHEMBL621226 | 1.00 | IKBKB (1.00) | IKBKBCHUKBTKCSF1RAURKA | |
| SCHEMBL618944 | 0.91 | IKBKB (0.83) | IKBKBCHUKBTKCSF1RAURKA | |
| SCHEMBL621398 | 0.91 | IKBKB (0.83) | IKBKBCHUKBTKCSF1RAURKA | |
| SCHEMBL621227 | 0.91 | IKBKB (0.83) | IKBKBCHUKBTKCSF1RAURKA | |
| SCHEMBL618651 | 0.91 | IKBKB (1.00) | IKBKBCHUKBTKCSF1RAURKA | |
| SCHEMBL621522 | 0.85 | IKBKB (0.77) | IKBKBCHUKBTKCSF1RAURKA | |
| SCHEMBL621812 | 0.85 | IKBKB (0.77) | IKBKBCHUKBTKCSF1RAURKA | |
| SCHEMBL621954 | 0.85 | IKBKB (1.00) | IKBKBCHUKBTKCSF1RAURKA | |
| SCHEMBL620632 | 0.84 | IKBKB (0.88) | IKBKBCHUKBTKCSF1RAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3521301-B1 | POLYAMIDE COMPOUND AND USE THEREOF | SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN) | 2024-03-06 | — | — | EP | claimed |
| US-12486293-B2 | Chirality sensing with molecular click chemistry probes | GEORGETOWN UNIVERSITY (US) | 2025-12-02 | — | — | US | disclosed |
| US-12215100-B2 | Anticancer compounds | PHARMA MAR, S.A. (ES) | 2025-02-04 | — | — | US | disclosed |
| US-20240353322-A1 | COMBINED DETERMINATION OF THE CONCENTRATION AND ENANTIOMERIC COMPOSITION OF CHIRAL COMPOUNDS USING SINGLE CHIROPTICAL ASSAY | GEORGETOWN UNIVERSITY | 2024-10-24 | — | — | US | disclosed |
| US-20240299329-A1 | PRECURSOR COMPOUNDS FOR PROVIDING RETINOIDS OF THE VATAMIN A5 PATHWAY AND USES THEREOF | UNIV OF DEBRECEN (HU) | 2024-09-12 | — | — | US | disclosed |
| US-20240287023-A1 | MACROCYCLIC COMPOUNDS AND COMPOSITIONS, AND METHODS OF PREPARING AND USING THE SAME | KURA ONCOLOGY INC (US) | 2024-08-29 | — | — | US | disclosed |
| US-20240248028-A1 | QUANTITATIVE CHIRALITY AND CONCENTRATION SENSING OF CHIRAL ANALYTES USING QUINONES, (HETERO)ARYL ISOCYANATES, AND/OR (HETERO)ARYL ISOTHIOCYANATES | GEORGETOWN UNIVERSITY | 2024-07-25 | — | — | US | disclosed |
| US-12029715-B2 | Precursor compounds for providing retinoids of the vitamin A5 pathway and uses thereof | UNIVERSITY OF DEBRECEN (HU) | 2024-07-09 | — | — | US | disclosed |
| US-12018011-B2 | Macrocyclic compounds and compositions, and methods of preparing and using the same | KURA ONCOLOGY, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| US-20230322711-A1 | MACROCYCLIC COMPOUNDS AND COMPOSITIONS, AND METHODS OF PREPARING AND USING THE SAME | WUXI APPTEC (HONG KONG) LIMITED (CN) | 2023-10-12 | — | — | US | disclosed |
| US-20120040958-A1 | INDOLE CARBOXAMIDES AS IKK2 INHIBITORS | GLAXOSMITHKLINE LLC | 2012-02-16 | — | — | US | disclosed |
| US-8071584-B2 | Indole carboxamides as IKK2 inhibitors | GLAXOSMITHKLINE LLC (US) | 2011-12-06 | — | — | US | disclosed |
| US-8071584-B2 | Indole carboxamides as IKK2 inhibitors | GLAXOSMITHKLINE LLC (US) | 2011-12-06 | — | — | US | disclosed |
| US-8071584-B2 | Indole carboxamides as IKK2 inhibitors | GLAXOSMITHKLINE LLC (US) | 2011-12-06 | — | — | US | disclosed |
| US-20100130468-A1 | INDOLE CARBOXAMIDES AS IKK2 INHIBITORS | GLAXOSMITHKLINE LLC | 2010-05-27 | — | — | US | disclosed |
| US-20100130468-A1 | INDOLE CARBOXAMIDES AS IKK2 INHIBITORS | GLAXOSMITHKLINE LLC | 2010-05-27 | — | — | US | disclosed |
| US-20100130468-A1 | INDOLE CARBOXAMIDES AS IKK2 INHIBITORS | GLAXOSMITHKLINE LLC | 2010-05-27 | — | — | US | disclosed |
| EP-2139322-A1 | INDOLE CARBOXAMIDES AS IKK2 INHIBITORS | Smithkline Beecham Corporation (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008118724-A1 | INDOLE CARBOXAMIDES AS IKK2 INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-02 | — | — | WO | disclosed |
| WO-2008118724-A1 | INDOLE CARBOXAMIDES AS IKK2 INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12029715-B2 | Precursor compounds for providing retinoids of the vitamin A5 pathway and uses thereof | RXRA, RXRG, RARA | IKBKB 2260/4885CHUK 1709/4885BTK 4847/4885 |
| US-12018011-B2 | Macrocyclic compounds and compositions, and methods of preparing and using the same | FNTA, FDPS, GGPS1 | IKBKB 2551/4885CHUK 2342/4885BTK 3791/4885 |
| US-20230322711-A1 | MACROCYCLIC COMPOUNDS AND COMPOSITIONS, AND METHODS OF PREPARING AND USING THE SAME | FNTA, FDPS, GGPS1 | IKBKB 2551/4885CHUK 2342/4885BTK 3791/4885 |
| US-20240287023-A1 | MACROCYCLIC COMPOUNDS AND COMPOSITIONS, AND METHODS OF PREPARING AND USING THE SAME | FNTA, FDPS, GGPS1 | IKBKB 2551/4885CHUK 2342/4885BTK 3791/4885 |
| US-20120040958-A1 | INDOLE CARBOXAMIDES AS IKK2 INHIBITORS | IDO2, IDO1, NFKBIA | IKBKB 8/4885CHUK 14/4885BTK 595/4885 |
| US-20100130468-A1 | INDOLE CARBOXAMIDES AS IKK2 INHIBITORS | IDO2, IDO1, NFKBIA | IKBKB 8/4885CHUK 14/4885BTK 589/4885 |
| US-20240299329-A1 | PRECURSOR COMPOUNDS FOR PROVIDING RETINOIDS OF THE VATAMIN A5 PATHWAY AND USES THEREOF | RXRA, RARA, RXRG | IKBKB 3091/4885CHUK 2454/4885BTK 4873/4885 |
| US-12486293-B2 | Chirality sensing with molecular click chemistry probes | PTMS, NISCH, CHAMP1 | IKBKB 3212/4885CHUK 2645/4885BTK 60/4885 |
| US-12215100-B2 | Anticancer compounds | TP53, MCL1, MYC | IKBKB 1180/4885CHUK 855/4885BTK 4285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.