Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Tetrahydrofuran. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL78660 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL4475590 | 0.86 | — | — | |
| Ethylene SCHEMBL2047134 | 0.84 | — | — | |
| SCHEMBL3842777 | 0.84 | — | — | |
| Bromide SCHEMBL4480968 | 0.84 | — | — | |
| Fluoride Ion SCHEMBL1130833 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL3682818 | 0.82 | TDP1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL3774056 | 0.81 | ACHE (0.33) | LMNA | |
| Hydrochloric Acid SCHEMBL3671969 | 0.81 | ACHE (0.33) | LMNA | |
| Hydrochloric Acid SCHEMBL21854563 | 0.81 | ACHE (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213304-B1 | Supported metallocene catalyst and the preparation process thereof | CHINA PETROLEUM & CHEMICAL (CN) | 2005-03-09 | — | — | EP | disclosed |
| EP-1213304-A1 | Supported metallocene catalyst and the preparation process thereof | China Petroleum & Chemical Corporation (CN) | 2002-06-12 | — | — | EP | disclosed |