Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.33 |
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.32 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | TACR2 | P21452 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL616915 | 1.00 | ACHE (0.33) | ACHELIPGBACE1PTGS2ESR1 | |
| Hydrochloric Acid SCHEMBL3774056 | 1.00 | ACHE (0.33) | ACHELIPGBACE1PTGS2ESR1 | |
| Hydrochloric Acid SCHEMBL21854563 | 1.00 | ACHE (0.33) | ACHELIPGBACE1PTGS2ESR1 | |
| Hydrochloric Acid SCHEMBL1477552 | 1.00 | ACHE (0.33) | ACHELIPGBACE1PTGS2ESR1 | |
| Hydrochloric Acid SCHEMBL3682818 | 0.98 | TDP1 (0.30) | ACHELIPGBACE1 | |
| Hydrochloric Acid SCHEMBL78660 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL4475590 | 0.91 | — | — | |
| Ethylene SCHEMBL2047134 | 0.89 | — | — | |
| SCHEMBL3842777 | 0.89 | — | — | |
| Fluoride Ion SCHEMBL1130833 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323524-B2 | Tandem tetramerisation-polymerisation of olefins | SASOL TECHNOLOGY (PTY) LIMITED (ZA) | 2008-01-29 | — | — | US | claimed |
| US-20060128910-A1 | Tandem tetramerisation-polymerisation of olefins | SASOL TECHNOLOGY (PTY) LIMITED (ZA) | 2006-06-15 | — | — | US | claimed |
| US-8227392-B2 | Base stocks and lubricant blends containing poly-alpha olefins | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2012-07-24 | — | — | US | disclosed |
| US-20100323937-A1 | Base stocks and lubricant blends containing poly-alpha olefins | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2010-12-23 | — | — | US | disclosed |
| EP-1517928-B1 | SUPPORTED HYBRID METALLOCENE CATALYST, METHOD FOR PREPARING THE SAME, AND METHOD FOR PREPARING POLYOLEFIN USING THE SAME | LG CHEMICAL LTD (KR) | 2010-11-10 | — | — | EP | disclosed |
| US-20090131705-A1 | Practical, Cost-Effective Synthesis of Ubiquinones | ZYMES, LLC | 2009-05-21 | — | — | US | disclosed |
| EP-1968608-A2 | PRACTICAL, COST-EFFECTIVE SYNTHESIS OF UBIQUINONES | Zymes, LLC (US) | 2008-09-17 | — | — | EP | disclosed |
| US-20080086013-A1 | CARBOMETALLATION OF ALKYNES AND IMPROVED SYNTHESIS OF UNIQUINONES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-04-10 | — | — | US | disclosed |
| WO-2008019196-A2 | CARBOMETALLATION OF ALKYNES AND IMPROVED SYNTHSIS OF UBIQUINONES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-02-14 | — | — | WO | disclosed |
| US-7323524-B2 | Tandem tetramerisation-polymerisation of olefins | SASOL TECHNOLOGY (PTY) LIMITED (ZA) | 2008-01-29 | — | — | US | disclosed |
| US-7294600-B2 | Supported hybrid metallocene catalyst, method for preparing the same, and method for preparing polyolefin using the same | LG CHEM, LTD. (KR) | 2007-11-13 | — | — | US | disclosed |
| US-5567777-A | CONTAINING AN ALPHA-OLEFIN; TRANSPARENCY | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-22 | — | — | US | disclosed |
| US-5567776-A | BLEND ELASTOMERIC COPOLYMERS CONTAINING ALPHA- AND CYCLO-OLEFINS; IMPACT STRENGTH, TRANSPARENCY, FIBER OPTICS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-22 | — | — | US | disclosed |
| EP-0691354-A1 | Unsaturated copolymer of ethylene and process for preparing the same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-10 | — | — | EP | disclosed |
| US-5470919-A | Seals with ozone resistance, heat aging resistance, oil resistance and weatherproofing | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0638594-A1 | Chlorinated ethylene/alpha-olefin copolymer rubber and composition containing the same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |
| EP-0597119-A1 | CYCLOOLEFIN COPOLYMER COMPOSITION AND PRODUCTION THEREOF | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1994-05-18 | — | — | EP | disclosed |
| EP-0303519-B1 | POLYMERIZATION OF ETHYLENE | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |
| US-4931517-A | Polymerization of ethylene | MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) | 1990-06-05 | — | — | US | disclosed |
| EP-0303519-A1 | Polymerization of ethylene | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080086013-A1 | CARBOMETALLATION OF ALKYNES AND IMPROVED SYNTHESIS OF UNIQUINONES | NDUFA10, NDUFB10, NDUFV1 | ACHE 2797/4885SLC6A2 2973/4885SLC6A3 2411/4885 |
| US-20090131705-A1 | Practical, Cost-Effective Synthesis of Ubiquinones | SQOR, NDUFS6, NDUFS5 | ACHE 1412/4885SLC6A2 1929/4885SLC6A3 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.