Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310825 | 0.87 | GABRA1 (0.61) | GABRA1CA1CA2GABRB2GABRG2 | |
| SCHEMBL524689 | 0.77 | HPGD (0.64) | GABRA1CA1CA2GABRB2GABRG2 | |
| SCHEMBL23250717 | 0.76 | GABRA1 (0.61) | GABRA1CA1CA2GABRB2GABRG2 | |
| SCHEMBL385724 | 0.74 | LMNA (0.55) | GABRA1CA1CA2GABRB2GABRG2 | |
| SCHEMBL14354371 | 0.74 | ERN1 (0.53) | GABRA1CA1CA2GABRB2GABRG2 | |
| SCHEMBL23258800 | 0.74 | GABRA1 (0.59) | GABRA1CA1CA2GABRB2GABRG2 | |
| SCHEMBL23258468 | 0.74 | GABRA1 (0.59) | GABRA1CA1CA2GABRB2GABRG2 | |
| Propofol SCHEMBL36245 | 0.73 | GABRA1 (1.00) | GABRA1CA1CA2GABRB2GABRG2 | |
| Propofol SCHEMBL2414429 | 0.73 | GABRA1 (1.00) | GABRA1CA1CA2GABRB2GABRG2 | |
| SCHEMBL548216 | 0.73 | TSHR (0.45) | GABRA1CA1CA2GABRB2GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1536759-A1 | ORAL CARE COMPOSITION COMPRISING TROPOLONE COMPOUNDS AND ESSENTIAL OILS | Warner-Lambert Company LLC (US) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004012692-A1 | ORAL CARE COMPOSITION COMPRISING TROPOLONE COMPOUNDS AND ESSENTIAL OILS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-12 | — | — | WO | disclosed |