Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6214075 | 0.82 | P2RX7 (0.42) | EPHX2ALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL6215690 | 0.79 | WNT3A (0.47) | ALDH1A1KMT2AKDM4EGAATSHR | |
| SCHEMBL6216012 | 0.76 | DRD4 (0.41) | ALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL7248437 | 0.76 | MAPK1 (0.47) | ALDH1A1KMT2AGAARAB9A | |
| SCHEMBL6212381 | 0.76 | MEN1 (0.46) | ALDH1A1KMT2AKDM4EGAARAB9A | |
| SCHEMBL6210153 | 0.75 | WNT3A (0.43) | KMT2A | |
| SCHEMBL6212034 | 0.75 | CYP1A2 (0.41) | ALDH1A1KMT2AGAARAB9A | |
| SCHEMBL6214919 | 0.75 | KMT2A (0.43) | ALDH1A1KMT2AGAATSHRNPC1 | |
| SCHEMBL6209953 | 0.73 | WNT3A (0.42) | ALDH1A1 | |
| SCHEMBL6211122 | 0.73 | MEN1 (0.43) | KMT2AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | claimed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | claimed |