Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6215690 | 0.86 | WNT3A (0.47) | TRPV1KMT2AMEN1NPC1TSHR | |
| SCHEMBL7248437 | 0.81 | MAPK1 (0.47) | MAPTKMT2AMEN1RAB9ACYP1A2 | |
| SCHEMBL6212859 | 0.79 | DRD2 (0.45) | KDRKMT2AMEN1NPC1HPGD | |
| SCHEMBL6216012 | 0.76 | DRD4 (0.41) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL6212381 | 0.75 | MEN1 (0.46) | MAPTKMT2AMEN1RAB9A | |
| SCHEMBL6210153 | 0.74 | WNT3A (0.43) | MAPTKMT2AMEN1 | |
| SCHEMBL6214919 | 0.74 | KMT2A (0.43) | KMT2AMEN1NPC1TSHRRAB9A | |
| SCHEMBL6212034 | 0.74 | CYP1A2 (0.41) | MAPTKMT2AMEN1RAB9ACYP1A2 | |
| SCHEMBL6214978 | 0.74 | EPHX2 (0.41) | KMT2ANPC1TSHRRAB9A | |
| SCHEMBL6214370 | 0.74 | DRD4 (0.45) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509213-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | Abbott Laboratories (US) | 2005-03-02 | — | — | EP | claimed |
| WO-2003099266-A2 | ACETAMIDES AND BENZAMIDES THAT ARE USEFUL IN TREATING SEXUAL DYSFUNCTION | ABBOTT LABORATORIES (US) | 2003-12-04 | — | — | WO | claimed |