Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10257627 | 0.87 | TSHR (0.42) | TP53TSHRPOLB | |
| SCHEMBL2736999 | 0.70 | POLB (0.38) | TP53TSHRPOLB | |
| SCHEMBL2736912 | 0.70 | ACACB (0.38) | TSHR | |
| SCHEMBL6181013 | 0.67 | ALDH1A1 (0.36) | TP53TSHRPOLB | |
| SCHEMBL10257325 | 0.65 | ACACB (0.49) | TSHRPOLB | |
| SCHEMBL2736897 | 0.65 | ACACB (0.42) | — | |
| SCHEMBL6184684 | 0.65 | RECQL (0.32) | TP53TSHRPOLB | |
| SCHEMBL6178624 | 0.65 | RIPK1 (0.52) | TSHR | |
| SCHEMBL13053751 | 0.62 | CTRB1 (0.38) | TSHRPOLB | |
| SCHEMBL10256466 | 0.61 | RIPK1 (0.61) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597223-A2 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | Esperion Therapeutics Inc. (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004067489-A2 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2004-08-12 | — | — | WO | disclosed |