Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NCF1 | P14598 | 1/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL590873 | 0.78 | KDM4E (0.68) | KDM4EMAPK1NPSR1LMNANCF1 | |
| SCHEMBL1147789 | 0.75 | KDM4E (0.64) | KDM4EMAPK1NPSR1LMNANCF1 | |
| Cyclopropane SCHEMBL28100553 | 0.75 | LMNA (0.91) | KDM4EMAPK1NPSR1LMNANCF1 | |
| SCHEMBL21878306 | 0.73 | KDM4E (0.70) | KDM4EMAPK1NPSR1LMNANCF1 | |
| SCHEMBL20541918 | 0.73 | KDM4E (0.70) | KDM4EMAPK1NPSR1LMNANCF1 | |
| SCHEMBL3688184 | 0.72 | ROCK2 (0.54) | KDM4EMAPK1NPSR1LMNANCF1 | |
| SCHEMBL6206052 | 0.72 | NCF1 (0.66) | KDM4EMAPK1NPSR1LMNANCF1 | |
| SCHEMBL6215190 | 0.71 | KDM4E (0.59) | KDM4EMAPK1NPSR1LMNANCF1 | |
| SCHEMBL592287 | 0.71 | KDM4E (0.80) | KDM4EMAPK1NPSR1LMNASLC22A12 | |
| SCHEMBL592288 | 0.71 | KDM4E (0.80) | KDM4EMAPK1NPSR1LMNASLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1551829-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004035569-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2004-04-29 | — | — | WO | disclosed |