Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 19/20 | 0.71 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6216466 | 0.97 | MTNR1A (0.72) | MTNR1AMTNR1BUSP2ALOX15TSHR | |
| SCHEMBL5355604 | 0.91 | MTNR1A (0.70) | MTNR1AMTNR1B | |
| SCHEMBL7015784 | 0.90 | MTNR1A (0.87) | MTNR1AMTNR1B | |
| SCHEMBL5349367 | 0.88 | MTNR1A (0.71) | MTNR1AMTNR1B | |
| SCHEMBL5344020 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL7019293 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL7020835 | 0.80 | MTNR1A (0.71) | MTNR1AMTNR1BHSD17B10 | |
| SCHEMBL5346051 | 0.80 | MTNR1A (0.74) | MTNR1AMTNR1BUSP2ALOX15TSHR | |
| SCHEMBL6216634 | 0.79 | MTNR1A (0.96) | MTNR1AMTNR1B | |
| SCHEMBL7016626 | 0.79 | MTNR1A (0.96) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317413-B1 | SUBSTITUTED BIPHENYL DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2005-08-24 | — | — | EP | disclosed |
| EP-1317413-A1 | SUBSTITUTED BIPHENYL DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002022555-A1 | SUBSTITUTED BIPHENYL DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2002-03-21 | — | — | WO | disclosed |