Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6212398 | 0.99 | AKR1C3 (0.37) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL6217020 | 0.83 | CYP2C19 (0.42) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6217243 | 0.82 | CYP2C19 (0.44) | AKR1C3AKR1C2MAPTMEN1KMT2A | |
| SCHEMBL6218459 | 0.81 | ALDH1A1 (0.42) | MAPTMEN1KMT2AALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL6215812 | 0.81 | ALDH1A1 (0.42) | MAPTMEN1KMT2AALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL6218147 | 0.79 | LMNA (0.37) | ALDH1A1GAARXFP1RAB9ALMNA | |
| SCHEMBL6216347 | 0.74 | KDM4E (0.43) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL6212224 | 0.72 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL6212921 | 0.72 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL7847368 | 0.71 | SLC6A4 (0.38) | AKR1C3AKR1C2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129690-B1 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | OREAL (FR) | 2005-01-05 | — | — | EP | claimed |
| EP-1129690-A2 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | L'OREAL (FR) | 2001-09-05 | — | — | EP | claimed |
| EP-1129690-B1 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | OREAL (FR) | 2005-01-05 | — | — | EP | disclosed |
| EP-1129690-A2 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | L'OREAL (FR) | 2001-09-05 | — | — | EP | disclosed |