Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218162 | 0.90 | ALDH1A1 (0.37) | MAPK1KMT2AL3MBTL1ALDH1A1HTT | |
| SCHEMBL6216922 | 0.88 | ENPP2 (0.34) | MAPK1KMT2AL3MBTL1FABP4 | |
| SCHEMBL6217553 | 0.86 | ENPP2 (0.34) | KMT2A | |
| SCHEMBL6220677 | 0.85 | POLB (0.40) | L3MBTL1FABP4ALDH1A1LMNAHTT | |
| SCHEMBL6199129 | 0.84 | MAPK1 (0.37) | MAPK1KMT2AL3MBTL1FABP4ALDH1A1 | |
| SCHEMBL6219884 | 0.81 | ITGAL (0.40) | KMT2A | |
| SCHEMBL6262430 | 0.81 | POLB (0.35) | L3MBTL1ALDH1A1LMNAHTT | |
| SCHEMBL6265119 | 0.80 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL6197609 | 0.79 | ITGAL (0.40) | KMT2AFABP4ALDH1A1 | |
| SCHEMBL6218779 | 0.78 | NPC1 (0.45) | KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140814-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2005-05-25 | — | — | EP | claimed |