SCHEMBL6218211

SCHEMBL6218211

CCCCCCCCCCCCCCCCOCCOC1OC(COCc2ccccc2)C(OCc2ccccc2)C(OCc2ccccc2)C1OCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ SSTR4 P31391 10/20 0.62
▸ SSTR1 P30872 6/20 0.62
▸ SSTR2 P30874 6/20 0.62
▸ SSTR3 P32745 6/20 0.62
▸ SSTR5 P35346 6/20 0.62
▸ TACR1 P25103 2/20 0.53
▸ ADRB2 P07550 1/20 0.53
▸ PTPN1 P18031 3/20 0.47
▸ CDC25B P30305 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8577146 0.94 SSTR4 (0.63) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL10781141 0.87 SSTR1 (0.71) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL10781148 0.87 SSTR1 (0.71) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL21148461 0.85 SSTR1 (0.52) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL20019530 0.85 SSTR1 (0.52) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL6890979 0.85 SSTR1 (0.52) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL26273937 0.83 SSTR1 (0.53) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL21080964 0.83 SSTR1 (0.46) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL6229615 0.83 SSTR4 (0.76) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL6545135 0.83 SSTR1 (0.60) SSTR4SSTR1SSTR2SSTR3SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6908989-B2 Process for the production of perbenzylated 1-O-glycosides SCHERING AG (DE) 2005-06-21 — — US disclosed
EP-1397376-B1 METHOD FOR PRODUCING PERBENZYLATED 1-O-GLYCOSIDES SCHERING AG (DE) 2005-05-04 — — EP disclosed
EP-1404691-B1 METHOD FOR PRODUCING PERACYLATED 1-O-GLYCOSIDES SCHERING AG (DE) 2005-03-09 — — EP disclosed
US-6831164-B2 Generation of peracylated 1-O-glycosides; obtain chemical intermediate, react with alkylating agent, heat and recover product SCHERING AKTIENGESELLSCHAFT (DE) 2004-12-14 — — US disclosed
EP-1397376-A1 METHOD FOR PRODUCING PERBENZYLATED 1-O-GLYCOSIDES SCHERING AKTIENGESELLSCHAFT (DE) 2004-03-17 — — EP disclosed
EP-1261614-B1 METHOD FOR THE PRODUCTION OF PERBENZYLATED 1-O GLYCOSIDES SCHERING AG (DE) 2004-01-07 — — EP disclosed
US-20030069402-A1 Process for the production of peracylated 1-0-glycosides SCHERING AG (DE) 2003-04-10 — — US disclosed
US-6545135-B2 Alkylation SCHERING AKTIENGESELLSCHAFT (DE) 2003-04-08 — — US disclosed
US-20030055242-A1 Process for the production of perbenzylated 1-O-glycosides BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2003-03-20 — — US disclosed
WO-2002102816-A1 METHOD FOR PRODUCING PERBENZYLATED 1-O-GLYCOSIDES SCHERING AKTIENGESELLSCHAFT (DE) 2002-12-27 — — WO disclosed
US-20020002274-A1 Process for the production of perbenzylated 1-0-glycosides SCHERING AKTIENGESELLSCHAFT 2002-01-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030055242-A1 Process for the production of perbenzylated 1-O-glycosides MAN1B1, STT3B, OSTC SSTR4 4291/4885SSTR1 4350/4885SSTR2 4469/4885
US-20030069402-A1 Process for the production of peracylated 1-0-glycosides B3GNT2, UGT8, UGGT1 SSTR4 4323/4885SSTR1 4101/4885SSTR2 4124/4885
US-20020002274-A1 Process for the production of perbenzylated 1-0-glycosides STT3B, MAN1B1, OSTC SSTR4 4009/4885SSTR1 4065/4885SSTR2 3996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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