Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6215386 | 0.82 | LMNA (0.43) | LMNANPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL6215650 | 0.79 | LMNA (0.41) | LMNANPC1RAB9AGAASMN1; SMN2 | |
| SCHEMBL6214221 | 0.79 | LMNA (0.41) | LMNANPC1RAB9AGAA | |
| SCHEMBL4198423 | 0.71 | LMNA (0.56) | LMNANPC1RAB9AGAAALDH1A1 | |
| SCHEMBL27656222 | 0.71 | LMNA (0.56) | LMNANPC1RAB9AGAACYP2C9 | |
| SCHEMBL8176193 | 0.71 | MAPK10 (0.35) | LMNASMN1; SMN2MEN1ALDH1A1MAPT | |
| SCHEMBL6217897 | 0.70 | GAA (0.41) | LMNANPC1RAB9AGAA | |
| SCHEMBL14344387 | 0.67 | HPD (0.50) | LMNANPC1RAB9AGAA | |
| SCHEMBL6218087 | 0.67 | LMNA (0.40) | LMNANPC1RAB9AGAA | |
| SCHEMBL30102436 | 0.67 | LMNA (0.55) | LMNANPC1RAB9AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140845-B1 | SUSBSTITUTED PYRIDINE HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-02-23 | — | — | EP | disclosed |
| US-6673938-B1 | Substituted pyridine herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-06 | — | — | US | disclosed |
| US-6534445-B1 | Pyridine ketones for controlling weeds | SYNGENTA PARTICIPATIONS AG (CH) | 2003-03-18 | — | — | US | disclosed |
| US-20030040437-A1 | Substituted pyridine herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2003-02-27 | — | — | US | disclosed |
| EP-1140845-A1 | SUSBSTITUTED PYRIDINE HERBICIDES | Syngenta Participations AG (CH) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039094-A1 | SUBSTITUTED PYRIDINE HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030040437-A1 | Substituted pyridine herbicides | DDT, CYP1A1, CYP1B1 | LMNA 3619/4885NPC1 4516/4885RAB9A 3251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.