⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20738821 | 1.00 | — | — | |
| SCHEMBL6849396 | 0.90 | — | — | |
| SCHEMBL4652997 | 0.83 | ALOX15 (0.33) | — | |
| SCHEMBL22821839 | 0.83 | ALOX15 (0.33) | — | |
| SCHEMBL30140053 | 0.83 | ALOX15 (0.33) | — | |
| SCHEMBL8984071 | 0.79 | ALOX15 (0.30) | — | |
| SCHEMBL23094005 | 0.77 | CES2 (0.46) | — | |
| SCHEMBL17860716 | 0.77 | CES2 (0.46) | — | |
| SCHEMBL1678731 | 0.75 | ALOX15 (0.32) | — | |
| SCHEMBL7850745 | 0.75 | ALOX15 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100254904-A1 | Novel therapeutic delivery systems | BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. | 2010-10-07 | — | — | US | claimed |
| US-6479034-B1 | Method of preparing gas and gaseous precursor-filled microspheres | BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. | 2002-11-12 | — | — | US | claimed |
| US-20020159952-A1 | Novel acoustically active drug delivery systems | BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. | 2002-10-31 | — | — | US | claimed |
| US-6443898-B1 | Therapeutic delivery systems | IMARX PHARMACEUTICAL CORP. | 2002-09-03 | — | — | US | claimed |
| EP-0981333-A4 | NOVEL ACOUSTICALLY ACTIVE DRUG DELIVERY SYSTEMS | IMARX PHARMACEUTICAL CORP (US) | 2002-04-24 | — | — | EP | claimed |
| US-6071495-A | TEMPERATURE ACTIVATED; PARTICULARLY USEFUL, FOR EXAMPLE, IN ULTRASONIC IMAGING APPLICATIONS AND IN THERAPEUTIC DRUG DELIVERY SYSTEMS. | IMARX PHARMACEUTICAL CORP. (US) | 2000-06-06 | — | — | US | claimed |
| EP-0981333-A1 | NOVEL ACOUSTICALLY ACTIVE DRUG DELIVERY SYSTEMS | IMARX PHARMACEUTICAL CORP. (US) | 2000-03-01 | — | — | EP | claimed |
| US-5853752-A | Methods of preparing gas and gaseous precursor-filled microspheres | IMARX PHARMACEUTICAL CORP. (US) | 1998-12-29 | — | — | US | claimed |
| WO-1998051284-A1 | NOVEL ACOUSTICALLY ACTIVE DRUG DELIVERY SYSTEMS | IMARX PHARMACEUTICAL CORP. (US) | 1998-11-19 | — | — | WO | claimed |
| EP-0802788-A4 | NOVEL THERAPEUTIC DELIVERY SYSTEMS | UNGER EVAN C (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0712293-A4 | METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES | UNGER EVAN C (US) | 1998-05-06 | — | — | EP | claimed |
| EP-0802788-A1 | NOVEL THERAPEUTIC DELIVERY SYSTEMS | UNGER, Evan C (US) | 1997-10-29 | — | — | EP | claimed |
| US-5585112-A | TEMPERATURE-ACTIVATED FLUORINE-CONTAINING GAS; USEFUL IN ULTRASONIC IMAGING AND DRUG DELIVERY SYSTEMS; FDA ORANGE BOOK LISTED PATENT FOR PERFLUTREN | IMARX PHARMACEUTICAL CORP. (US) | 1996-12-17 | — | — | US | claimed |
| EP-0712293-A1 | METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES | UNGER, Evan C (US) | 1996-05-22 | — | — | EP | claimed |
| WO-1994028780-A2 | METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES | UNGER EVAN C (US) | 1994-12-22 | — | — | WO | claimed |
| WO-1994028874-A1 | NOVEL THERAPEUTIC DELIVERY SYSTEMS | UNGER EVAN C (US) | 1994-12-22 | — | — | WO | claimed |
| EP-2514387-B1 | ULTRASONIC DRUG DELIVERY SYSTEM FOR DENTAL USE | NAT CT GERIATRICS & GERONTOLOGY (JP) | 2018-03-21 | — | — | EP | disclosed |
| US-9452036-B2 | Dental ultrasonic drug delivery system and dental ultrasonic drug delivery method | NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY (JP) | 2016-09-27 | — | — | US | disclosed |
| WO-1994028780-A2 | METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES | UNGER EVAN C (US) | 1994-12-22 | — | — | WO | disclosed |
| WO-1994028874-A1 | NOVEL THERAPEUTIC DELIVERY SYSTEMS | UNGER EVAN C (US) | 1994-12-22 | — | — | WO | disclosed |