SCHEMBL17860716

SCHEMBL17860716

CCCCCCC(F)(F)I

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.46
LPAR1 Q92633 1/20 0.46
LPAR3 Q9UBY5 1/20 0.46
GGPS1 O95749 3/20 0.44
TSHR P16473 2/20 0.44
THRB P10828 1/20 0.44
ALDH1A1 P00352 1/20 0.41
EPHX1 P07099 1/20 0.40
FAAH O00519 7/20 0.39
CES1 P23141 5/20 0.39
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39
FDPS P14324 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23094005 1.00 CES2 (0.46) CES2LPAR1LPAR3GGPS1TSHR
SCHEMBL23093979 0.97
SCHEMBL23093966 0.88
SCHEMBL24820838 0.77 CES2 (0.42) CES2LPAR1LPAR3GGPS1TSHR
SCHEMBL24234728 0.77 CES2 (0.50) CES2LPAR1LPAR3GGPS1TSHR
SCHEMBL20738821 0.77
SCHEMBL12348014 0.77 TSHR (0.50) CES2LPAR1LPAR3GGPS1TSHR
SCHEMBL23139281 0.77 CES2 (0.50) CES2LPAR1LPAR3GGPS1TSHR
SCHEMBL22268768 0.77 CES2 (0.50) CES2LPAR1LPAR3GGPS1TSHR
SCHEMBL23034519 0.77 CES2 (0.50) CES2LPAR1LPAR3GGPS1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12545759-B2 Method of producing fluorine-containing compound and method of producing copolymer AGC Inc. (JP) 2026-02-10 US disclosed
US-12528896-B2 Fluorine-containing polymer and method of producing same AGC Inc. (JP) 2026-01-20 US disclosed
US-12486343-B2 Method for producing iodine-containing compound, and iodine-containing compound AGC Inc. (JP) 2025-12-02 US disclosed
EP-4029848-B1 METHOD FOR PRODUCING FLUORINE-CONTAINING COMPOUND AND METHOD FOR PRODUCING COPOLYMER AGC INC (JP) 2025-07-09 EP disclosed
CN-114402001-B Method for producing fluorine-containing compound and method for producing copolymer AGC株式会社 2023-10-27 CN disclosed
EP-4212553-A1 METHOD FOR PRODUCING IODINE-CONTAINING COMPOUND, AND IODINE-CONTAINING COMPOUND AGC INC. (JP) 2023-07-19 EP disclosed
US-20230203215-A1 METHOD FOR PRODUCING IODINE-CONTAINING COMPOUND, AND IODINE-CONTAINING COMPOUND AGC Inc. (JP) 2023-06-29 US disclosed
EP-4105247-A1 FLUORINE-CONTAINING POLYMER AND METHOD FOR PRODUCING SAME AGC INC. (JP) 2022-12-21 EP disclosed
US-20220389132-A1 FLUORINE-CONTAINING POLYMER AND METHOD OF PRODUCING SAME AGC Inc. (JP) 2022-12-08 US disclosed
CN-115087677-A Fluorine-containing polymer and method for producing same AGC株式会社 2022-09-20 CN disclosed
EP-4029848-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING COMPOUND AND METHOD FOR PRODUCING COPOLYMER AGC INC. (JP) 2022-07-20 EP disclosed
US-20220195099-A1 METHOD OF PRODUCING FLUORINE-CONTAINING COMPOUND AND METHOD OF PRODUCING COPOLYMER AGC Inc. (JP) 2022-06-23 US disclosed
CN-114402001-A Process for producing fluorine-containing compound and process for producing copolymer AGC株式会社 2022-04-26 CN disclosed
WO-2021161851-A1 METHOD FOR PRODUCING IODINE-CONTAINING COMPOUND, AND POLYMER AGC株式会社 2021-08-19 WO disclosed
WO-2021161852-A1 FLUORINE-CONTAINING POLYMER AND METHOD FOR PRODUCING SAME AGC株式会社 2021-08-19 WO disclosed
WO-2021049455-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING COMPOUND AND METHOD FOR PRODUCING COPOLYMER AGC株式会社 2021-03-18 WO disclosed
WO-2016100578-A2 ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS MICURX PHARMACEUTICALS, INC. (US) 2016-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545759-B2 Method of producing fluorine-containing compound and method of producing copolymer PYM1, FLI1, F11 CES2 325/4885LPAR1 2002/4885LPAR3 2704/4885
US-20230203215-A1 METHOD FOR PRODUCING IODINE-CONTAINING COMPOUND, AND IODINE-CONTAINING COMPOUND SSTR2, TPO, BRI3BP CES2 819/4885LPAR1 4668/4885LPAR3 4387/4885
US-12486343-B2 Method for producing iodine-containing compound, and iodine-containing compound SSTR2, TPO, BRI3BP CES2 819/4885LPAR1 4668/4885LPAR3 4387/4885
US-12528896-B2 Fluorine-containing polymer and method of producing same TPO, EEF1D, F7 CES2 524/4885LPAR1 3220/4885LPAR3 3495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.