Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2759010 | 0.87 | NPC1 (0.61) | POLBNPC1RAB9AATMCNR1 | |
| SCHEMBL26661392 | 0.85 | POLB (0.67) | POLBNPC1RAB9AATMCYP2C9 | |
| SCHEMBL4516395 | 0.85 | POLB (0.71) | POLBNPC1RAB9ACYP2C9SMN1; SMN2 | |
| SCHEMBL7575404 | 0.85 | POLB (0.61) | POLBNPC1RAB9AATMCYP2C9 | |
| SCHEMBL1484964 | 0.83 | EPHX1 (0.71) | POLBCYP2C9SMN1; SMN2EPHX1GAA | |
| SCHEMBL24263392 | 0.83 | POLB (1.00) | POLBNPC1RAB9ACYP2C9SMN1; SMN2 | |
| SCHEMBL9623645 | 0.83 | POLB (0.69) | POLBNPC1RAB9AATMCYP2C9 | |
| SCHEMBL3025327 | 0.83 | POLB (0.69) | POLBNPC1RAB9ACYP2C9SMN1; SMN2 | |
| SCHEMBL6023280 | 0.83 | NPC1 (0.54) | POLBNPC1RAB9AATMCNR1 | |
| SCHEMBL706443 | 0.83 | HDAC1 (0.58) | POLBNPC1RAB9AATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103608350-A | Triazolopyridine compounds | BAYER IP GMBH | 2014-02-26 | — | — | CN | claimed |
| CN-121270417-A | Synthesis method of N- (hydroxy-2-methylpropan-2-yl) benzamide compound | 马鞍山诺恩特医药科技有限公司 | 2026-01-06 | — | — | CN | disclosed |
| CN-121270417-A | Synthesis method of N- (hydroxy-2-methylpropan-2-yl) benzamide compound | 马鞍山诺恩特医药科技有限公司 | 2026-01-06 | — | — | CN | disclosed |
| EP-2603098-B1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED (US) | 2025-08-06 | — | — | EP | disclosed |
| CN-116162084-A | Pyran derivatives as CYP11A1 inhibitors | 奥赖恩公司 | 2023-05-26 | — | — | CN | disclosed |
| US-11129397-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | FIREMENICH INCORPORATED (US) | 2021-09-28 | — | — | US | disclosed |
| CN-107365319-B | Modulation of chemosensory receptors and ligands associated therewith | 弗门尼舍公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-106107406-B | Methods of improving the stability of sweetness enhancers and compositions comprising stable sweetness enhancers | 弗门尼舍公司 | 2020-06-09 | — | — | CN | disclosed |
| CN-110115365-A | The adjusting that actinism receptor and relative ligand are carried out | 西诺米克斯公司 | 2019-08-13 | — | — | CN | disclosed |
| US-20190208802-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED | 2019-07-11 | — | — | US | disclosed |
| US-6610837-B1 | Preparation of an oligonucleotide compound of given formula by reacting with given compounds, followed by oxidation or sulfurization | ISIS PHARMACEUTICALS, INC. | 2003-08-26 | — | — | US | disclosed |
| US-6121437-A | SYNTHESIS OF OLIGONUCLEOTIDES USING OLIGONUCLEOTIDES OR NUCLEOTIDES WITH PROTECTED INTERNUCLEOSIDIC PHOSPHORUS FUNCTIONALITIES WHICH CAN BE REMOVED UNDER MILD CONDITIONS AND PRODUCE NONTOXIC BY-PRODUCTS | ISIS PHARMACEUTICALS, INC. (US) | 2000-09-19 | — | — | US | disclosed |
| US-4900725-A | CONTRACEPTIVES | ROUSSEL UCLAF (FR) | 1990-02-13 | — | — | US | disclosed |
| EP-0262188-A1 | STEROIDS COMPRISING A SPIRANIC CYCLE IN POSITION 17, PREPARATION PROCESS AND UTILIZATION THEREOF. | ROUSSEL UCLAF (FR) | 1988-04-06 | — | — | EP | disclosed |
| WO-1987005908-A1 | STEROIDS COMPRISING A SPIRANIC CYCLE IN POSITION 17, PREPARATION PROCESS AND UTILIZATION THEREOF | ROUSSEL-UCLAF (FR) | 1987-10-08 | — | — | WO | disclosed |
| US-4171452-A | FUNGICIDES | INTERX RESEARCH CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |
| US-4132805-A | Novel soft N-chloroamino alcohol derivatives exhibiting antibacterial activity | INTERX RESEARCH CORPORATION (US) | 1979-01-02 | — | — | US | disclosed |
| US-4115588-A | Antibacterial novel soft n-chloroamino alcohol derivatives | INTERX RESEARCH CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
| US-4092420-A | Novel soft N-chloroamino alcohol derivatives exhibiting antibacterial activity | INTERX RESEARCH CORPORATION (US) | 1978-05-30 | — | — | US | disclosed |
| US-4036843-A | ANTIBACTERIAL | INTERX RESEARCH CORPORATION (US) | 1977-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11129397-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | TFEB, TREH, SLC2A8 | POLB 2203/4885NPC1 1999/4885RAB9A 2396/4885 |
| US-20190208802-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | POLB 2203/4885NPC1 1999/4885RAB9A 2396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.