Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22832225 | 0.85 | POLB (0.50) | POLBCYP2C9NPSR1SMN1; SMN2EPHX1 | |
| SCHEMBL22832224 | 0.85 | POLB (0.50) | POLBCYP2C9NPSR1SMN1; SMN2EPHX1 | |
| SCHEMBL621869 | 0.85 | POLB (0.71) | POLBCYP2C9NPSR1SMN1; SMN2EPHX1 | |
| SCHEMBL12301905 | 0.83 | ALDH1A1 (0.53) | POLBSMN1; SMN2GAAKMT2ARAB9A | |
| SCHEMBL9828829 | 0.81 | POLB (0.57) | POLBCYP2C9NPSR1SMN1; SMN2EPHX1 | |
| SCHEMBL9828824 | 0.81 | POLB (0.57) | POLBCYP2C9NPSR1SMN1; SMN2EPHX1 | |
| SCHEMBL14552910 | 0.80 | KMT2A (0.50) | POLBNPSR1KMT2AALOX15CYP2C19 | |
| SCHEMBL16475559 | 0.80 | POLB (0.55) | POLBCYP2C9NPSR1SMN1; SMN2EPHX1 | |
| SCHEMBL408310 | 0.79 | CYP2C9 (0.67) | POLBCYP2C9SMN1; SMN2EPHX1GAA | |
| SCHEMBL26661392 | 0.78 | POLB (0.67) | POLBCYP2C9NPSR1SMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969585-B2 | Method for producing optically active compound or salt thereof | NAGASAKI UNIVERSITY (JP) | 2015-03-03 | — | — | US | disclosed |
| US-8969585-B2 | Method for producing optically active compound or salt thereof | NAGASAKI UNIVERSITY (JP) | 2015-03-03 | — | — | US | disclosed |
| US-20140012010-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND OR SALT THEREOF | NAGASAKI UNIVERSITY (JP) | 2014-01-09 | — | — | US | disclosed |
| US-20140012010-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND OR SALT THEREOF | NAGASAKI UNIVERSITY (JP) | 2014-01-09 | — | — | US | disclosed |
| WO-2002055077-A1 | USE OF IMIDAZOLYL CYCLIC ACETAL DERIVATIVES IN THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF DISEASES MEDIATED BY THE ALK5 RECEPTORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140012010-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND OR SALT THEREOF | MINK1, MELK, MRPL21 | POLB 4228/4885CYP2C9 1362/4885NPSR1 1659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.