Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 13/20 | 0.49 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14827254 | 0.87 | P4HTM (0.51) | KDM4EALDH1A1L3MBTL1MEN1LMNA | |
| SCHEMBL25790388 | 0.83 | PARP1 (0.40) | L3MBTL1LMNAMAPTMAPK1 | |
| SCHEMBL6717442 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1L3MBTL1MEN1LMNA | |
| SCHEMBL30181544 | 0.79 | P4HTM (0.53) | KDM4EALDH1A1L3MBTL1MEN1LMNA | |
| SCHEMBL6920475 | 0.79 | P4HTM (0.53) | KDM4EALDH1A1L3MBTL1MEN1LMNA | |
| SCHEMBL10095109 | 0.78 | P4HTM (0.53) | KDM4EALDH1A1L3MBTL1MEN1LMNA | |
| SCHEMBL27837540 | 0.78 | P4HTM (0.52) | KDM4EALDH1A1L3MBTL1MEN1LMNA | |
| SCHEMBL20178617 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1L3MBTL1MEN1LMNA | |
| SCHEMBL24859291 | 0.76 | ESR1 (0.38) | ALDH1A1L3MBTL1LMNACYP1A2CYP3A4 | |
| SCHEMBL14358092 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1L3MBTL1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159569-A1 | DUAL HDAC6/PROTEASOME INHIBITORS, AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-05-25 | — | — | US | disclosed |
| US-9765018-B2 | IDO inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-19 | — | — | US | disclosed |
| US-20130237415-A1 | SAFENER COMPOSITIONS AND METHODS FOR REDUCING MYCOTOXINS | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-12 | — | — | US | disclosed |
| EP-2592931-A1 | SAFENER COMPOSITIONS AND METHODS FOR REDUCING MYCOTOXINS | Syngenta Participations AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012021250-A1 | SAFENER COMPOSITIONS AND METHODS FOR REDUCING MYCOTOXINS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159569-A1 | DUAL HDAC6/PROTEASOME INHIBITORS, AND METHODS OF USE THEREOF | HDAC6, PSMG3, PSMB2 | KDM4E 1954/4885ALDH1A1 2269/4885L3MBTL1 1442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.