Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 13/20 | 0.53 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30181544 | 1.00 | P4HTM (0.53) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL27837540 | 0.86 | P4HTM (0.52) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL2627835 | 0.85 | EGLN1 (0.56) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL19441050 | 0.85 | P4HTM (0.50) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL14358092 | 0.85 | KDM4E (0.53) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL25523204 | 0.85 | P4HTM (0.50) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL8150961 | 0.84 | NPC1 (0.44) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL18740089 | 0.83 | P4HTM (0.49) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| SCHEMBL6652918 | 0.83 | P4HTM (0.49) | P4HTMP4HA1MIFKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL20539069 | 0.83 | P4HTM (0.49) | P4HTMP4HA1MIFKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145259-A2 | EP2 ANTAGONIST COMPOUNDS | RESERVOIR NEUROSCIENCE, INC. (US) | 2024-07-04 | — | — | WO | disclosed |
| US-20230159569-A1 | DUAL HDAC6/PROTEASOME INHIBITORS, AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230159569-A1 | DUAL HDAC6/PROTEASOME INHIBITORS, AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-05-25 | — | — | US | disclosed |
| WO-2022272060-A1 | EP2 ANTAGONIST COMPOUNDS | RESERVOIR NEUROSCIENCE, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| US-20220411432-A1 | MDM2 PROTEIN DEGRADERS | UNIV MICHIGAN REGENTS (US) | 2022-12-29 | — | — | US | disclosed |
| US-11192898-B2 | MDM2 protein degraders | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2021-12-07 | — | — | US | disclosed |
| US-20210323970-A1 | METHOD FOR PRODUCING A SPIROOXINDOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2021-10-21 | — | — | US | disclosed |
| CN-113329996-A | Compounds and methods for treating hedgehog pathway related disorders | 苏州麦迪耐斯医药科技有限公司 | 2021-08-31 | — | — | CN | disclosed |
| US-10865216-B2 | Tricyclic Gyrase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2020-12-15 | — | — | US | disclosed |
| US-10851111-B2 | Method for producing a spirooxindole derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2020-12-01 | — | — | US | disclosed |
| US-20100048557-A1 | Triazolopyridine JAK Inhibitor Compounds and Methods | GENENTECH, INC. | 2010-02-25 | — | — | US | disclosed |
| US-20100035875-A1 | TRIAZOLOPYRIDINE JAK INHIBITOR COMPOUNDS AND METHODS | GENENTECH, INC. | 2010-02-11 | — | — | US | disclosed |
| US-20090270412-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. | 2009-10-29 | — | — | US | disclosed |
| US-20090270412-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. | 2009-10-29 | — | — | US | disclosed |
| US-20090239854-A1 | Tetracyclic compounds | MEDIVATION TECHNOLOGIES, INC. | 2009-09-24 | — | — | US | disclosed |
| US-20090239854-A1 | Tetracyclic compounds | MEDIVATION TECHNOLOGIES, INC. | 2009-09-24 | — | — | US | disclosed |
| US-20090186830-A1 | MACROCYCLES AND THEIR USES | NOVARTIS AG (CH) | 2009-07-23 | — | — | US | disclosed |
| US-20080146811-A1 | Compounds and Methods For Treatment of Thrombosis | DAIICHI ASUBIO MEDICAL RESEARCH LABORATORIES LLC | 2008-06-19 | — | — | US | disclosed |
| WO-2006012504-A2 | COMPOUNDS AND METHODS FOR TREATMENT OF THROMBOSIS | DAIAMED, INC. (US) | 2006-02-02 | — | — | WO | disclosed |
| WO-1984004302-A1 | SUBSTITUTED PICOLINIC ACIDS, PROCESSES FOR THEIR PREPARATION, THEIR USE AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1984-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11192898-B2 | MDM2 protein degraders | MDM2, TP53, TP53BP1 | P4HTM 3169/4885P4HA1 936/4885MIF 1175/4885 |
| US-20100048557-A1 | Triazolopyridine JAK Inhibitor Compounds and Methods | JAK2, JAK1, JAK3 | P4HTM 1591/4885P4HA1 1187/4885MIF 3624/4885 |
| US-20080146811-A1 | Compounds and Methods For Treatment of Thrombosis | F2, SERPINC1, PLAT | P4HTM 375/4885P4HA1 246/4885MIF 4540/4885 |
| US-20230159569-A1 | DUAL HDAC6/PROTEASOME INHIBITORS, AND METHODS OF USE THEREOF | HDAC6, PSMG3, PSMB2 | P4HTM 2516/4885P4HA1 1455/4885MIF 4052/4885 |
| US-20090270412-A1 | PYRIDO[3,4-B]INDOLES AND METHODS OF USE | HTR3B, HTR4, HTR2C | P4HTM 563/4885P4HA1 1223/4885MIF 3485/4885 |
| US-20220411432-A1 | MDM2 PROTEIN DEGRADERS | MDM2, TP53, TP53BP1 | P4HTM 3169/4885P4HA1 936/4885MIF 1175/4885 |
| US-20090186830-A1 | MACROCYCLES AND THEIR USES | CYP11B2, OAT, CYP27A1 | P4HTM 1684/4885P4HA1 2402/4885MIF 1517/4885 |
| US-20210323970-A1 | METHOD FOR PRODUCING A SPIROOXINDOLE DERIVATIVE | MDM2, TP53, RB1 | P4HTM 4214/4885P4HA1 3133/4885MIF 1477/4885 |
| US-10851111-B2 | Method for producing a spirooxindole derivative | MDM2, TP53, RB1 | P4HTM 4214/4885P4HA1 3133/4885MIF 1477/4885 |
| US-20090239854-A1 | Tetracyclic compounds | HTR2C, HTR3D, HTR5A | P4HTM 1005/4885P4HA1 1989/4885MIF 1521/4885 |
| US-20100035875-A1 | TRIAZOLOPYRIDINE JAK INHIBITOR COMPOUNDS AND METHODS | JAK2, JAK1, JAK3 | P4HTM 1591/4885P4HA1 1187/4885MIF 3624/4885 |
| US-10865216-B2 | Tricyclic Gyrase inhibitors | TOP1, TOP2A, TOP2B | P4HTM 3789/4885P4HA1 2121/4885MIF 3475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.