Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.49 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6219624 | 1.00 | LMNA (0.49) | LMNAMEN1KMT2AMAPTPLIN1 | |
| SCHEMBL11781170 | 0.86 | MAPT (0.66) | LMNAMEN1KMT2AMAPTPLIN1 | |
| SCHEMBL4778793 | 0.85 | MEN1 (0.57) | LMNAMEN1KMT2AMAPTPLIN1 | |
| SCHEMBL4778791 | 0.85 | MEN1 (0.57) | LMNAMEN1KMT2AMAPTPLIN1 | |
| SCHEMBL10084346 | 0.84 | MEN1 (0.53) | LMNAMEN1KMT2AMAPTPLIN1 | |
| SCHEMBL21065589 | 0.84 | KMT2A (0.51) | LMNAMEN1KMT2AMAPTPLIN1 | |
| SCHEMBL9680982 | 0.83 | KMT2A (0.50) | LMNAMEN1KMT2AMAPTPLIN1 | |
| SCHEMBL9680987 | 0.83 | KMT2A (0.50) | LMNAMEN1KMT2AMAPTPLIN1 | |
| SCHEMBL3123681 | 0.83 | MAPT (0.50) | LMNAMEN1KMT2AMAPTPLIN1 | |
| SCHEMBL6220713 | 0.83 | MAPT (0.50) | LMNAMEN1KMT2AMAPTPLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050165236-A1 | Process for the preparation of Imiquimod and intermediates thereof | DIPHARMA S.P.A. (IT) | 2005-07-28 | — | — | US | disclosed |
| EP-1529781-A1 | A process for the preparation of Imiquimod and intermediates thereof | Dipharma S.p.A. (IT) | 2005-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165236-A1 | Process for the preparation of Imiquimod and intermediates thereof | MYD88, TLR7, MAVS | LMNA 1417/4885MEN1 3638/4885KMT2A 1246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.