Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 7/20 | 0.49 |
| ▸ | ICAM1 | P05362 | 7/20 | 0.49 |
| ▸ | ITGAL | P20701 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6196912 | 0.86 | ITGB2 (0.57) | ITGB2ICAM1ITGALRAB9AKMT2A | |
| SCHEMBL6913718 | 0.81 | ITGB2 (0.56) | ITGB2ICAM1ITGALRAB9AKMT2A | |
| SCHEMBL6220318 | 0.81 | ITGB2 (0.47) | ITGB2ICAM1ITGALRAB9AKMT2A | |
| SCHEMBL6220880 | 0.79 | ITGB2 (0.53) | ITGB2ICAM1ITGALRAB9AKMT2A | |
| SCHEMBL6317251 | 0.76 | ITGB2 (0.71) | ITGB2ICAM1ITGALRAB9AKMT2A | |
| SCHEMBL7612170 | 0.72 | ITGB2 (0.55) | ITGB2ICAM1ITGALRAB9AKMT2A | |
| SCHEMBL7064969 | 0.71 | ITGB2 (0.49) | ITGB2ICAM1ITGALRAB9AKMT2A | |
| SCHEMBL6220454 | 0.71 | ITGB2 (0.42) | ITGB2ICAM1ITGALRAB9AKMT2A | |
| SCHEMBL6217665 | 0.71 | ITGB2 (0.48) | ITGB2ICAM1ITGALRAB9AKMT2A | |
| SCHEMBL6220298 | 0.71 | ITGB2 (0.45) | ITGB2ICAM1ITGALRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140814-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2005-05-25 | — | — | EP | claimed |