Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7213496 | 0.93 | P2RY12 (0.35) | MEN1ADORA2AADORA1DGAT1P2RY12 | |
| SCHEMBL7213537 | 0.88 | SELE (0.44) | MEN1P2RY12KMT2A | |
| SCHEMBL6220931 | 0.84 | ADORA2A (0.36) | MEN1ADORA2AADORA1KMT2A | |
| SCHEMBL6221794 | 0.83 | SIRT2 (0.38) | DGAT1 | |
| Hydrochloric Acid SCHEMBL6435657 | 0.81 | F10 (0.38) | ADORA2AADORA1 | |
| Trifluoroacetic Acid SCHEMBL7213497 | 0.81 | P2RY12 (0.36) | MEN1ADORA2AADORA1DGAT1P2RY12 | |
| Trifluoroacetic Acid SCHEMBL6221816 | 0.78 | SIRT2 (0.35) | MEN1DGAT1 | |
| SCHEMBL6221508 | 0.76 | F10 (0.49) | DGAT1 | |
| SCHEMBL7213538 | 0.72 | SELE (0.48) | MEN1ADORA2AADORA1KMT2A | |
| SCHEMBL1652680 | 0.72 | F10 (0.34) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086099-B1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-09-28 | — | — | EP | claimed |
| EP-1086099-B1 | SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-09-28 | — | — | EP | disclosed |