Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8675454 | 0.93 | TTR (0.52) | KEAP1NFE2L2MEN1KMT2AALDH1A1 | |
| SCHEMBL2402122 | 0.87 | TOP1 (0.41) | KEAP1NFE2L2MEN1KMT2AALDH1A1 | |
| SCHEMBL6036890 | 0.84 | ALDH1A1 (0.51) | KEAP1NFE2L2MEN1KMT2AALDH1A1 | |
| SCHEMBL2460415 | 0.81 | ELANE (0.54) | KEAP1NFE2L2MEN1KMT2AALDH1A1 | |
| SCHEMBL9509808 | 0.79 | ADORA2A (0.61) | KEAP1NFE2L2MEN1KMT2AALDH1A1 | |
| SCHEMBL28707279 | 0.79 | TYMS (0.47) | KEAP1NFE2L2MEN1KMT2AALDH1A1 | |
| SCHEMBL23212346 | 0.77 | TTR (0.57) | KEAP1NFE2L2MEN1KMT2AALDH1A1 | |
| SCHEMBL2137125 | 0.77 | FABP7 (0.39) | KMT2AALDH1A1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL11107244 | 0.77 | TTR (0.50) | KEAP1NFE2L2MEN1KMT2AALDH1A1 | |
| SCHEMBL11039554 | 0.76 | ELANE (0.55) | KEAP1NFE2L2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355898-B1 | METHOD FOR PRODUCING FLAVONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2005-10-12 | — | — | EP | disclosed |