Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 6/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5552765 | 0.72 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL6706747 | 0.71 | ALDH1A1 (0.64) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL5557953 | 0.70 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL6225092 | 0.69 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL16750287 | 0.69 | CNR2 (0.48) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL9278001 | 0.68 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL5559147 | 0.68 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| Hydrochloric Acid SCHEMBL9278006 | 0.67 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL6222754 | 0.67 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DCNR2 | |
| SCHEMBL16750284 | 0.66 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330455-B1 | NOVEL 7-AZAINDOLES, USE THEREOF AS PHOSPHODIESTERASE 4 INHIBITORS AND METHOD FOR PRODUCING THE SAME | ELBION AG (DE) | 2005-08-03 | — | — | EP | claimed |