Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6221756 | 0.86 | GAA (0.47) | GAAMAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL6222105 | 0.84 | GAA (0.51) | GAAMAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL13380458 | 0.82 | MAPT (0.54) | GAAMAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL5540075 | 0.81 | SMN1; SMN2 (0.40) | GAAMAPTALDH1A1KDM4EUSP2 | |
| SCHEMBL5540081 | 0.81 | ME3 (0.50) | GAAMAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL12074788 | 0.79 | MAPT (0.44) | GAAMAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL5537860 | 0.79 | VCP (0.40) | KDM4ESMN1; SMN2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL21783932 | 0.79 | KDM4E (0.45) | GAAMAPTALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL13769088 | 0.78 | CDK4 (0.45) | CDK4CDK6VCP | |
| SCHEMBL5924898 | 0.77 | HRH4 (0.47) | GAAMAPTALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1512684-A1 | use of derivative of para-phenylenediamine substituted by a homopiperidine ring, for the dyeing of keratinous fibres | L'OREAL (FR) | 2005-03-09 | — | — | EP | claimed |