Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | GFER | P55789 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725147 | 0.86 | ADRB1 (0.46) | MAPTGFERSMN1; SMN2KDM4EGAA | |
| SCHEMBL8725144 | 0.85 | HSP90AA1 (0.40) | MAPTGFERSMN1; SMN2KDM4EGAA | |
| SCHEMBL22837858 | 0.85 | HSP90AA1 (0.40) | MAPTGFERSMN1; SMN2KDM4EGAA | |
| SCHEMBL5537556 | 0.85 | ME3 (0.52) | MAPTGFERSMN1; SMN2KDM4EGAA | |
| SCHEMBL5537549 | 0.85 | SMN1; SMN2 (0.42) | MAPTGFERSMN1; SMN2KDM4EGAA | |
| SCHEMBL13798544 | 0.84 | CHRNA7 (0.50) | SMN1; SMN2KMT2AL3MBTL1MEN1POLB | |
| SCHEMBL5535481 | 0.83 | HSP90AA1 (0.41) | MAPTGFERSMN1; SMN2KDM4EGAA | |
| Benzene SCHEMBL27474247 | 0.82 | ME3 (0.57) | MAPTGFERSMN1; SMN2KDM4EGAA | |
| SCHEMBL8729299 | 0.82 | SMN1; SMN2 (0.40) | MAPTGFERSMN1; SMN2KDM4EGAA | |
| SCHEMBL6223263 | 0.82 | GAA (0.47) | MAPTGFERSMN1; SMN2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2172461-A1 | DI(ARYLAMINO)ARYL COMPOUND | Astellas Pharma Inc. (JP) | 2010-04-07 | — | — | EP | disclosed |