Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230117 | 0.87 | NR3C1 (0.38) | — | |
| SCHEMBL4432730 | 0.76 | NR3C1 (0.32) | — | |
| SCHEMBL6226627 | 0.74 | NR3C1 (0.35) | — | |
| SCHEMBL6226237 | 0.73 | MCL1 (0.35) | MCL1P2RX7 | |
| SCHEMBL5389781 | 0.70 | NR3C1 (0.39) | — | |
| SCHEMBL5518605 | 0.69 | NR3C1 (0.52) | — | |
| SCHEMBL18682073 | 0.64 | GABRA2 (0.46) | — | |
| SCHEMBL4437967 | 0.63 | NR3C1 (0.38) | — | |
| SCHEMBL3652176 | 0.63 | NR3C1 (0.39) | — | |
| SCHEMBL6230116 | 0.63 | NR3C1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511716-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2005-03-09 | — | — | EP | claimed |
| WO-2003101932-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-12-11 | — | — | WO | claimed |