Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 7/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ESRRB | O95718 | 1/20 | 0.38 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL483970 | 0.84 | ESR2 (0.55) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| Hydrochloric Acid SCHEMBL7794275 | 0.83 | ESR2 (0.53) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL20480300 | 0.82 | MEN1 (0.37) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL20480301 | 0.82 | MEN1 (0.37) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL25284715 | 0.77 | KDM4E (0.38) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL30499285 | 0.77 | BACE1 (0.57) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL11973788 | 0.77 | BACE1 (0.57) | ALDH1A1MEN1KMT2ACASP1CASP7 | |
| SCHEMBL2133059 | 0.76 | NR4A2 (0.54) | CYP1A2PDGFRBPDGFRA | |
| SCHEMBL30506415 | 0.76 | NR4A2 (0.54) | CYP1A2PDGFRBPDGFRA | |
| SCHEMBL5958458 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2ACASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037266-A | Antibacterial chloroxoquinoline derivative | WANG ZIHOU | 2015-11-11 | — | — | CN | claimed |
| CN-105017145-A | Chloroxoquinoline derivative with anti-tumor activity | WANG ZIHOU | 2015-11-04 | — | — | CN | claimed |
| CN-103864680-A | Chloroxoquinoline derivative with antineoplastic activity | WANG ZIHOU | 2014-06-18 | — | — | CN | claimed |
| CN-103864681-A | Chloroxoquinoline derivatives for antibacterial use | WANG ZIHOU | 2014-06-18 | — | — | CN | claimed |
| EP-0056765-B1 | PREPARATION OF 4-HYDROXYQUINOLINES | RHONE-POULENC SANTE (FR) | 1985-06-19 | — | — | EP | claimed |
| EP-0056765-A1 | Preparation of 4-hydroxyquinolines | RHONE-POULENC SANTE (FR) | 1982-07-28 | — | — | EP | claimed |
| CN-121426745-A | Burisperidone Synthesis method of intermediate | 鲁南制药集团股份有限公司 | 2026-01-30 | — | — | CN | disclosed |
| CN-119661537-A | Nucleoside compound, preparation method thereof, composition thereof and application of nucleoside compound in medicine | 中国科学院上海药物研究所 | 2025-03-21 | — | — | CN | disclosed |
| EP-3833668-B1 | PRMT5 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2025044876-A1 | ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | 海宁奕诺炜特科技有限公司 | 2025-03-06 | — | — | WO | disclosed |
| CN-114057815-B | Novel 6-6 bicyclic aromatic ring substituted nucleosides as PRMT5 inhibitors | 詹森药业有限公司 | 2025-02-25 | — | — | CN | disclosed |
| WO-2024238406-A1 | FUROPYRIDINE COMPOUNDS AS P53 MUTANT STABILIZER AND USES THEREOF | FRONTIER MEDICINES CORPORATION (US) | 2024-11-21 | — | — | WO | disclosed |
| US-12145961-B2 | Spirobicyclic analogues | JANSSEN PHARMACEUTICA NV (BE) | 2024-11-19 | — | — | US | disclosed |
| WO-2004014871-A1 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2004-02-19 | — | — | WO | disclosed |
| EP-0097585-B1 | PROCESS FOR THE PREPARATION OF 4-HYDROXY QUINOLINES | RHONE-POULENC SANTE (FR) | 1986-03-26 | — | — | EP | disclosed |
| EP-0056765-B1 | PREPARATION OF 4-HYDROXYQUINOLINES | RHONE-POULENC SANTE (FR) | 1985-06-19 | — | — | EP | disclosed |
| EP-0056766-B1 | PROCESS FOR THE PREPARATION OF 4-AMINO-CHLOROQUINOLINES | RHONE-POULENC SANTE (FR) | 1984-05-16 | — | — | EP | disclosed |
| EP-0097585-A1 | Process for the preparation of 4-hydroxy quinolines | RHONE-POULENC SANTE (FR) | 1984-01-04 | — | — | EP | disclosed |
| EP-0056765-A1 | Preparation of 4-hydroxyquinolines | RHONE-POULENC SANTE (FR) | 1982-07-28 | — | — | EP | disclosed |
| EP-0056766-A1 | Process for the preparation of 4-amino-chloroquinolines | RHONE-POULENC SANTE (FR) | 1982-07-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12145961-B2 | Spirobicyclic analogues | PRMT5, HDAC5, SIRT5 | ALDH1A1 1492/4885MEN1 849/4885KMT2A 251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.