Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.30 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
| ▸ | PMM2 | O15305 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28451753 | 0.84 | ALDH1A1 (0.37) | ALDH1A1TDP1TSHRPTGER4TYMS | |
| SCHEMBL29686335 | 0.80 | VCP (0.40) | VCPALDH1A1HIF1AVCAM1TDP1 | |
| SCHEMBL22687129 | 0.80 | ALDH1A1 (0.38) | ALDH1A1HIF1AVCAM1TDP1ATM | |
| SCHEMBL16739101 | 0.80 | VCP (0.40) | VCPALDH1A1HIF1AVCAM1TDP1 | |
| SCHEMBL8817806 | 0.78 | TDP1 (0.47) | ALDH1A1HIF1AVCAM1TDP1ATM | |
| SCHEMBL30159235 | 0.77 | GRIN2D (0.41) | VCPALDH1A1HIF1AVCAM1TDP1 | |
| SCHEMBL30297073 | 0.77 | PTGER4 (0.48) | VCPALDH1A1HIF1AVCAM1TDP1 | |
| SCHEMBL20797684 | 0.77 | PTGER4 (0.48) | VCPALDH1A1HIF1AVCAM1TDP1 | |
| SCHEMBL102949 | 0.77 | S100A4 (0.40) | VCPALDH1A1HIF1AVCAM1TDP1 | |
| SCHEMBL2463690 | 0.77 | GRIN2D (0.41) | VCPALDH1A1HIF1AVCAM1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553075-A1 | LPA RECEPTOR ANTAGONISTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-07-13 | — | — | EP | disclosed |