SCHEMBL622758

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL620825	0.86	KDM4E (0.44)	KDM4EALDH1A1TSHRMAPTHSD17B10
	SCHEMBL623187	0.85	TP53 (0.39)	KDM4EALDH1A1HSD17B10LRRK2NPSR1
	SCHEMBL623275	0.85	MAPK14 (0.48)	MAPTRECQLLRRK2PDGFRB
	SCHEMBL624015	0.83	KDM4E (0.52)	KDM4EALDH1A1TSHRMAPTHSD17B10
	SCHEMBL624510	0.83	MAPT (0.44)	KDM4EALDH1A1TSHRMAPTHSD17B10
	SCHEMBL622523	0.82	KDM4E (0.52)	KDM4EALDH1A1TSHRMAPTHSD17B10
	SCHEMBL623282	0.81	KDM4E (0.52)	KDM4EALDH1A1TSHRMAPTHSD17B10
	SCHEMBL624158	0.80	ENPP2 (0.54)	KDM4EALDH1A1TSHRMAPTHSD17B10
	SCHEMBL624464	0.80	KMT2A (0.54)	KDM4EALDH1A1MAPTLMNAHTT
	SCHEMBL624097	0.79	LMNA (0.45)	KDM4EALDH1A1MAPTHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.