Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | FADS1 | O60427 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10505019 | 0.80 | IDO1 (0.42) | IDO1PDPK1CYP11B2MAOAMAOB | |
| SCHEMBL9183567 | 0.75 | CYP11B2 (0.53) | IDO1PDPK1CYP11B2MAOAMAOB | |
| Bicarbonate SCHEMBL11600214 | 0.73 | PIN1 (0.40) | IDO1PDPK1CYP11B2MAOAMAOB | |
| SCHEMBL1697825 | 0.73 | IDO1 (0.46) | IDO1PDPK1CYP11B2MAOAMAOB | |
| Hydrochloric Acid SCHEMBL20843623 | 0.72 | IDO1 (0.47) | IDO1PDPK1CYP11B2MAOAMAOB | |
| SCHEMBL4139877 | 0.72 | IDO1 (0.44) | IDO1PDPK1CYP11B2HTR6 | |
| SCHEMBL13198513 | 0.72 | DRD2 (0.50) | IDO1PDPK1CYP11B2MAOAMAOB | |
| SCHEMBL4139874 | 0.72 | IDO1 (0.44) | IDO1PDPK1CYP11B2HTR6 | |
| SCHEMBL4139879 | 0.72 | IDO1 (0.44) | IDO1PDPK1CYP11B2HTR6 | |
| SCHEMBL18242239 | 0.72 | IDO1 (0.44) | IDO1PDPK1CYP11B2HTR6CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050182269-A1 | Process for the preparation of 3-cyano-1-naphthoic acid and some analogues thereof | ASTRAZENECA AB (SE) | 2005-08-18 | — | — | US | disclosed |
| EP-1517884-A1 | A PROCESS FOR THE PREPARATION OF 3-CYANO-1-NAPHTHOIC ACID AND SOME ANALOGUES THEREOF | AstraZeneca AB (SE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000792-A1 | A PROCESS FOR THE PREPARATION OF 3-CYANO-1-NAPHTHOIC ACID AND SOME ANALOGUES THEREOF | ASTRAZENECA AB (SE) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182269-A1 | Process for the preparation of 3-cyano-1-naphthoic acid and some analogues thereof | CYP8B1, CYP51A1, NISCH | IDO1 823/4885PDPK1 2415/4885CYP11B2 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.