Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6228833 | 1.00 | ALDH1A1 (0.71) | ALDH1A1KCNH3PRSS1F2PRSS2 | |
| SCHEMBL11264649 | 0.88 | ALDH1A1 (0.53) | ALDH1A1HTTTDP1CASP1 | |
| SCHEMBL4862764 | 0.87 | ALDH1A1 (0.71) | ALDH1A1KCNH3PRSS1F2PRSS2 | |
| SCHEMBL4858474 | 0.87 | ALDH1A1 (0.71) | ALDH1A1KCNH3PRSS1F2PRSS2 | |
| SCHEMBL11443275 | 0.86 | ALDH1A1 (0.54) | ALDH1A1HTTTDP1CASP1 | |
| Hydrochloric Acid SCHEMBL4854566 | 0.86 | ALDH1A1 (0.69) | ALDH1A1KCNH3PRSS1F2PRSS2 | |
| Hydrochloric Acid SCHEMBL4854362 | 0.86 | ALDH1A1 (0.69) | ALDH1A1KCNH3PRSS1F2PRSS2 | |
| SCHEMBL4863422 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KCNH3PRSS1F2PRSS2 | |
| SCHEMBL29262271 | 0.85 | ABL1 (0.53) | ALDH1A1KCNH3PRSS1F2PRSS2 | |
| SCHEMBL8159092 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HTTABL1TDP1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496046-A1 | New coupling components | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-01-12 | — | — | EP | disclosed |