Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11443275 | 0.98 | ALDH1A1 (0.54) | ALDH1A1HTTTDP1CASP1MAPT | |
| SCHEMBL6227906 | 0.88 | ALDH1A1 (0.71) | ALDH1A1HTTTDP1CASP1 | |
| SCHEMBL6228833 | 0.88 | ALDH1A1 (0.71) | ALDH1A1HTTTDP1CASP1 | |
| SCHEMBL6342530 | 0.84 | ALDH1A1 (0.54) | ALDH1A1HTTTDP1MAPTCYP3A4 | |
| SCHEMBL15928722 | 0.81 | ALDH1A1 (0.43) | ALDH1A1HTTTDP1CASP1MAPT | |
| SCHEMBL20624882 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TDP1CYP3A4KDM4ESMN1; SMN2 | |
| SCHEMBL4466255 | 0.81 | ALDH1A1 (0.76) | ALDH1A1HTTTDP1MAPTCYP3A4 | |
| SCHEMBL29262271 | 0.79 | ABL1 (0.53) | ALDH1A1HTTTDP1CASP1 | |
| SCHEMBL8159092 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HTTTDP1CASP1MAPT | |
| SCHEMBL2455817 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HTTTDP1CASP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329504-A | COUPLERS FOR DYES, HAIR DYES | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-05-11 | — | — | US | disclosed |
| US-4125367-A | FOR KERATINIC FIBERS | L'OREAL (FR) | 1978-11-14 | — | — | US | disclosed |