Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11490122 | 0.91 | CA2 (0.43) | POLBNPSR1PIN1KMT2AMAPT | |
| SCHEMBL28189548 | 0.87 | POLB (0.52) | POLBNPSR1PIN1KMT2AMAPT | |
| SCHEMBL11626388 | 0.84 | TSHR (0.49) | POLBMAPTALDH1A1NPC1LMNA | |
| SCHEMBL11627716 | 0.84 | TSHR (0.51) | POLBKMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL11628964 | 0.83 | PARP10 (0.50) | POLBNPSR1KMT2AMAPTALDH1A1 | |
| SCHEMBL29035644 | 0.81 | CES1 (0.42) | POLBNPSR1KMT2AMAPTALDH1A1 | |
| SCHEMBL9437357 | 0.81 | PIN1 (0.53) | POLBNPSR1PIN1KMT2AMAPT | |
| SCHEMBL27313970 | 0.80 | PIN1 (0.49) | POLBNPSR1PIN1KMT2AMAPT | |
| SCHEMBL9437333 | 0.79 | MEN1 (0.51) | POLBNPSR1PIN1KMT2AMAPT | |
| SCHEMBL28458817 | 0.79 | SRC (0.66) | POLBNPSR1PIN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1525177-A1 | SUBSTITUTED 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES AND PREPARATION AND USES THEREOF | Genfit (FR) | 2005-04-27 | — | — | EP | disclosed |
| EP-1519908-A2 | COMPOSITION BASED ON SUBSTITUTED 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES, PREPARATION AND USES THEREOF | Genfit (FR) | 2005-04-06 | — | — | EP | disclosed |
| WO-2004005243-A2 | COMPOSITION BASED ON SUBSTITUTED 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES | GENFIT (FR) | 2004-01-15 | — | — | WO | disclosed |
| WO-2004005233-A1 | SUBSTITUTED 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES AND PREPARATION AND USES THEREOF | GENFIT (FR) | 2004-01-15 | — | — | WO | disclosed |
| US-5645973-A | Process for adjusting the sensitivity to radiation of photopolymerizable compositions | CIBA-GEIGY CORPORATION (US) | 1997-07-08 | — | — | US | disclosed |
| US-5573889-A | Process for adjusting the sensitivity to radiation of photopolymerizable compositions | CIBA-GEIGY CORPORATION (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0425440-B1 | Method of adjusting the photosensitivity of photopolymerizable compositions | CIBA GEIGY AG (CH) | 1994-11-17 | — | — | EP | disclosed |
| EP-0425440-A1 | Method of adjusting the photosensitivity of photopolymerizable compositions | CIBA-GEIGY AG (CH) | 1991-05-02 | — | — | EP | disclosed |
| US-4229274-A | PHOTOINITIATOR, PHOTOSENSITIZER, QUENCHER, AND COMPOUNDS CONTAINING ACRYLYLOXY GROUPS | PPG INDUSTRIES, INC. (US) | 1980-10-21 | — | — | US | disclosed |
| US-4088554-A | MONOKETALS OF ESTERS AND AMIDES OF AROMATIC ALPHA, BETA-DIOXOCARBOXYLIC ACID | CIBA-GEIGY CORPORATION (US) | 1978-05-09 | — | — | US | disclosed |