Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724136 | 0.77 | CYP2A6 (0.48) | CYP2A6CYP1A2KDM4ELMNATDP1 | |
| SCHEMBL27898649 | 0.76 | ATM (0.48) | CYP2A6CYP1A2KDM4ELMNAATM | |
| SCHEMBL7936307 | 0.67 | KDM4E (0.46) | CYP2A6CYP1A2KDM4ELMNATDP1 | |
| Iodide SCHEMBL4885250 | 0.66 | MAPT (0.49) | CYP2A6CYP1A2KDM4ELMNATDP1 | |
| SCHEMBL14344241 | 0.65 | KMT2A (0.46) | CYP2A6CYP1A2KDM4ELMNATDP1 | |
| SCHEMBL9373271 | 0.65 | RAB9A (0.38) | CYP2A6CYP1A2KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL13652061 | 0.64 | KDM4E (0.44) | CYP2A6CYP1A2KDM4ELMNATDP1 | |
| SCHEMBL10167906 | 0.63 | CYP1A2 (0.50) | CYP2A6CYP1A2KDM4ELMNATDP1 | |
| SCHEMBL29993495 | 0.63 | HTT (0.32) | TDP1SMN1; SMN2HTT | |
| SCHEMBL8350086 | 0.63 | CYP2A6 (0.44) | CYP2A6CYP1A2KDM4ELMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438318-B1 | TISSUE SPECIFIC FLUORESCENT CHELATES | UNIV TEXAS TECH (US) | 2005-11-09 | — | — | EP | disclosed |
| US-6962690-B2 | Tissue specific fluorescent chelates possessing long wavelength UV excitation | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-11-08 | — | — | US | disclosed |
| US-20030099598-A1 | Tissue specific fluorescent chelates possessing long wavelength UV excitation | DOW GLOBAL TECHNOLOGIES INC. | 2003-05-29 | — | — | US | disclosed |
| US-5112837-A | Inhibitors of thymidylate synthetase enzyme | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-12 | — | — | US | disclosed |
| EP-0318225-A2 | 6-Aryl aminomethyl quinoline derivatives and their use as anti-tumour agents | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030099598-A1 | Tissue specific fluorescent chelates possessing long wavelength UV excitation | DDB1, TNNC1, TRPC1 | CYP2A6 4240/4885CYP1A2 4388/4885KDM4E 3823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.