Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15682958 | 0.84 | FAAH (0.67) | FAAH | |
| SCHEMBL11055180 | 0.83 | FAAH (0.55) | FAAHCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10877406 | 0.82 | FAAH (0.50) | FAAHCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL12043581 | 0.82 | FAAH (0.46) | FAAH | |
| SCHEMBL2364382 | 0.81 | KIF11 (0.50) | FAAHALDH1A1 | |
| SCHEMBL10887890 | 0.81 | FAAH (0.49) | FAAHNPSR1KDM4EALDH1A1POLB | |
| SCHEMBL7606599 | 0.80 | NPC1 (0.45) | NPSR1 | |
| SCHEMBL1799848 | 0.80 | ACHE (0.56) | FAAHCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9126647 | 0.80 | ESR1 (0.53) | FAAHCYP3A4TSHRALDH1A1 | |
| SCHEMBL15765735 | 0.80 | KDM4E (0.57) | FAAHNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590321-A2 | ARYL ALKYL CARBAMATE DERIVATIVES PRODUCTION AND USE THEREOF IN THERAPY | Sanofi-Aventis (FR) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004067498-A2 | ARYL ALKYL CARBAMATE DERIVATIVES PRODUCTION AND USE THEREOF IN THERAPY | SANOFI-AVENTIS (FR) | 2004-08-12 | — | — | WO | disclosed |