Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4423855 | 0.73 | NOS3 (0.39) | ADORA2BGAA | |
| SCHEMBL2678381 | 0.73 | USP2 (0.33) | ADORA2BADORA1GAA | |
| SCHEMBL26860530 | 0.68 | ADORA2B (0.30) | ADORA2B | |
| SCHEMBL4279839 | 0.67 | IRAK4 (0.30) | — | |
| SCHEMBL21597737 | 0.66 | — | — | |
| SCHEMBL21604128 | 0.66 | NOS3 (0.33) | ADORA2B | |
| SCHEMBL7278528 | 0.64 | NOS2 (0.41) | ADORA2BADORA1GAA | |
| SCHEMBL4762534 | 0.64 | NOS2 (0.35) | — | |
| SCHEMBL5223298 | 0.63 | — | — | |
| SCHEMBL7272832 | 0.62 | NOS2 (0.44) | ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567517-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | Bayer Pharmaceuticals Corporation (US) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050651-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-06-17 | — | — | WO | disclosed |