Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1275928 | 0.78 | LMNA (0.50) | THRBLMNATP53 | |
| Ammonia Solution, Strong SCHEMBL18730207 | 0.76 | LMNA (0.48) | THRBLMNATP53 | |
| SCHEMBL23057360 | 0.74 | CA2 (0.44) | CA2 | |
| SCHEMBL12309862 | 0.73 | — | — | |
| SCHEMBL13430496 | 0.72 | THRB (0.50) | THRBLMNACA2 | |
| SCHEMBL8466316 | 0.72 | — | — | |
| SCHEMBL31298229 | 0.70 | THRB (0.42) | THRB | |
| SCHEMBL778902 | 0.69 | CA2 (0.33) | CA2 | |
| SCHEMBL8594256 | 0.69 | CA2 (0.33) | CA2 | |
| SCHEMBL18928 | 0.67 | THRB (1.00) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517876-A1 | METHOD FOR PRODUCING SUBSTITUTED ORGANIC COMPOUNDS AND USE OF CATALYSTS FOR SUBSTITUTION REACTIONS | Solvent Innovation GmbH (DE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2003106379-A1 | METHOD FOR PRODUCING SUBSTITUTED ORGANIC COMPOUNDS AND USE OF CATALYSTS FOR SUBSTITUTION REACTIONS | SOLVENT INNOVATION GMBH (DE) | 2003-12-24 | — | — | WO | disclosed |