Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 4/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5589234 | 0.75 | AGTR1 (0.39) | AGTR1NPC1RAB9AGAATNF | |
| SCHEMBL5589232 | 0.73 | AGTR1 (0.51) | AGTR1NPC1RAB9AGAATNF | |
| SCHEMBL11078493 | 0.70 | CES2 (0.58) | NPC1RAB9AGAAALDH1A1KDM4E | |
| SCHEMBL28038453 | 0.68 | KMT2A (0.51) | AGTR1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL27752173 | 0.66 | CES2 (0.45) | NPC1RAB9AGAAALDH1A1KDM4E | |
| SCHEMBL12901597 | 0.65 | HDAC3 (0.47) | NPC1RAB9AGAAALDH1A1KDM4E | |
| SCHEMBL28523378 | 0.65 | NPC1 (0.44) | NPC1RAB9ATNFKLF5NOD1 | |
| SCHEMBL12204551 | 0.65 | METAP2 (0.50) | NPC1RAB9AALDH1A1METAP2KDM4E | |
| SCHEMBL28038778 | 0.65 | KMT2A (0.66) | AGTR1NPC1RAB9AGAATNF | |
| SCHEMBL16473181 | 0.65 | KMT2A (0.60) | AGTR1NPC1RAB9AGAATNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | disclosed |