Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4346978 | 0.91 | MAPT (0.41) | MAPTRAB9ASLC6A9LMNAALDH1A1 | |
| SCHEMBL6225098 | 0.87 | MAPT (0.40) | MAPTLMNASMN1; SMN2POLBKDM4E | |
| SCHEMBL6226242 | 0.87 | SLC6A4 (0.41) | MAPTLMNAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL6227291 | 0.87 | SMN1; SMN2 (0.38) | MAPTALDH1A1SMN1; SMN2KDM4EFFAR1 | |
| SCHEMBL4351090 | 0.86 | LMNA (0.41) | MAPTRAB9ASLC6A9LMNAALDH1A1 | |
| SCHEMBL6227136 | 0.86 | LMNA (0.39) | MAPTRAB9ASLC6A9LMNAALDH1A1 | |
| SCHEMBL6226094 | 0.84 | KMT2A (0.51) | MAPTLMNAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL6226736 | 0.84 | MEN1 (0.41) | MAPTLMNAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4351072 | 0.84 | NOX4 (0.41) | MAPTRAB9ASLC6A9LMNAALDH1A1 | |
| SCHEMBL4345355 | 0.84 | PTPN1 (0.39) | MAPTRAB9ASLC6A9LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539683-A2 | PHENOL DERIVATIVES AND THEIR USE AS ROTAMASE INHIBITORS | Jerini AG (DE) | 2005-06-15 | — | — | EP | claimed |
| WO-2004026815-A2 | PHENOL DERIVATIVES AND THEIR USE AS ROTAMASE INHIBITORS | JERINI AG (DE) | 2004-04-01 | — | — | WO | claimed |