Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4346370 | 0.88 | CTSD (0.41) | LMNASMN1; SMN2POLBALDH1A1BLM | |
| SCHEMBL6227024 | 0.87 | SLC6A4 (0.42) | LMNASMN1; SMN2POLBALDH1A1BLM | |
| SCHEMBL4351799 | 0.87 | LMNA (0.40) | LMNASMN1; SMN2POLBALDH1A1BLM | |
| SCHEMBL6225937 | 0.86 | SLC6A4 (0.38) | LMNASMN1; SMN2POLBBLMMAPT | |
| SCHEMBL6671646 | 0.86 | DDR1 (0.38) | LMNASMN1; SMN2ALDH1A1BLMSLC6A4 | |
| SCHEMBL6230263 | 0.86 | MAPT (0.37) | LMNASMN1; SMN2POLBALDH1A1MAPT | |
| SCHEMBL4351061 | 0.84 | LMNA (0.40) | LMNASMN1; SMN2POLBALDH1A1BLM | |
| SCHEMBL6668436 | 0.83 | KMT2A (0.51) | LMNAPOLBMAPTSLC6A4KDM4E | |
| SCHEMBL4354635 | 0.83 | LMNA (0.44) | LMNASMN1; SMN2POLBALDH1A1BLM | |
| SCHEMBL6229113 | 0.82 | HTR1A (0.35) | LMNASMN1; SMN2POLBALDH1A1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539683-A2 | PHENOL DERIVATIVES AND THEIR USE AS ROTAMASE INHIBITORS | Jerini AG (DE) | 2005-06-15 | — | — | EP | claimed |
| WO-2004030664-A2 | NEW COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2004-04-15 | — | — | WO | claimed |
| WO-2004026815-A2 | PHENOL DERIVATIVES AND THEIR USE AS ROTAMASE INHIBITORS | JERINI AG (DE) | 2004-04-01 | — | — | WO | claimed |