Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.44 |
| ▸ | GLA | P06280 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 10/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | CASP7 | P55210 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31025577 | 0.71 | ALDH1A1 (0.61) | CA12CA9CA1KMT2AMEN1 | |
| SCHEMBL28932900 | 0.71 | ALDH1A1 (0.61) | CA12CA9CA1KMT2AMEN1 | |
| SCHEMBL17885121 | 0.71 | ALDH1A1 (0.63) | CA12CA9CA1KMT2AMEN1 | |
| SCHEMBL20974387 | 0.71 | LMNA (0.39) | KMT2AMEN1ALDH1A1KDM4EGLA | |
| SCHEMBL12618036 | 0.69 | AR (0.61) | CA12CA9CA1KMT2AMEN1 | |
| SCHEMBL31693361 | 0.68 | ALDH1A1 (0.62) | CA12CA9CA1KMT2AMEN1 | |
| SCHEMBL27587553 | 0.68 | KDM4E (0.59) | CA12CA9CA1KMT2AMEN1 | |
| SCHEMBL78691 | 0.68 | CA14 (0.41) | KMT2AMEN1KDM4EGAAHSD17B10 | |
| SCHEMBL483004 | 0.67 | KDM4E (0.61) | CA12CA9CA1KMT2AMEN1 | |
| SCHEMBL29403594 | 0.67 | KDM4E (0.61) | CA12CA9CA1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1595866-A1 | COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV | Sanwa Kagaku Kenkyusho Co., Ltd. (JP) | 2005-11-16 | — | — | EP | disclosed |