SCHEMBL6231104

SCHEMBL6231104

Nc1ccc(O)c(CN2CCNCC2)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.73
TSHR P16473 2/20 0.46
GFER P55789 1/20 0.46
BACE1 P56817 1/20 0.46
LMNA P02545 2/20 0.44
PRKCI P41743 1/20 0.44
MPO P05164 1/20 0.43
CACNA1B Q00975 1/20 0.43
SIGMAR1 Q99720 1/20 0.42
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
CYP1A2 P05177 1/20 0.40
CHRM2 P08172 1/20 0.40
SLC6A4 P31645 1/20 0.40
OPRD1 P41143 1/20 0.40
OPRK1 P41145 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7769915 0.98 ACHE (0.74) ACHETSHRGFERBACE1LMNA
SCHEMBL29565193 0.88 ACHE (0.86) ACHETSHRGFERBACE1LMNA
SCHEMBL126246 0.88 ACHE (0.86) ACHETSHRGFERBACE1LMNA
Hydrochloric Acid SCHEMBL5694431 0.86 ACHE (0.87) ACHETSHRGFERBACE1LMNA
SCHEMBL28837434 0.85 ACHE (1.00) ACHETSHRGFERBACE1PRKCI
SCHEMBL18753544 0.81 SMN1; SMN2 (0.50) ACHETSHRGFERBACE1LMNA
SCHEMBL922653 0.81 ACHE (0.73) ACHETSHRGFERBACE1LMNA
SCHEMBL22425608 0.81 LMNA (0.61) ACHETSHRGFERBACE1LMNA
SCHEMBL22791815 0.81 ACHE (0.73) ACHETSHRGFERBACE1LMNA
SCHEMBL18754006 0.81 ACHE (0.47) ACHETSHRGFERBACE1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114878540-A Derivatization reagents, kits and methods for detecting nerve agents 中国人民解放军军事科学院军事医学研究院 2022-08-09 CN disclosed
CN-100387225-C Tabletting method of thickening system HENKEL KGAA (DE) 2008-05-14 CN disclosed
EP-1292270-B1 Oxidative Dyeing Agent comprising 2-Hydroxy-5-Aminobenzyl-Piperazine as Developer HENKEL KGAA (DE) 2005-04-20 EP disclosed
EP-1292270-B1 Oxidative Dyeing Agent comprising 2-Hydroxy-5-Aminobenzyl-Piperazine as Developer HENKEL KGAA (DE) 2005-04-20 EP disclosed
CN-1411370-A Method for tabletting thickening system HENKEL KGAA (DE) 2003-04-16 CN disclosed
EP-1292270-A1 OXIDATION DYEING AGENT Henkel Kommanditgesellschaft auf Aktien (DE) 2003-03-19 EP disclosed
WO-2001097763-A2 OXIDATION DYEING AGENT CONTAINING 2-HYDROXY-5-AMINOBENZYL PIPERAZINES HENKEL KGAA (DE) 2001-12-27 WO disclosed