Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 5/20 | 0.42 |
| ▸ | FNTB | P49356 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6480491 | 1.00 | ALDH1A1 (0.51) | ALDH1A1ALOX15TSHRFNTAFNTB | |
| SCHEMBL6244701 | 0.82 | ALDH1A1 (0.49) | ALDH1A1ALOX15TSHRFNTAFNTB | |
| SCHEMBL9329872 | 0.82 | ALDH1A1 (0.49) | ALDH1A1ALOX15TSHRFNTAFNTB | |
| SCHEMBL6231134 | 0.79 | GRIK1 (0.44) | ALDH1A1ALOX15TSHRFNTAFNTB | |
| SCHEMBL6231140 | 0.79 | GRIK1 (0.44) | ALDH1A1ALOX15TSHRFNTAFNTB | |
| SCHEMBL1061282 | 0.79 | GRIK1 (0.44) | ALDH1A1ALOX15TSHRFNTAFNTB | |
| SCHEMBL1882200 | 0.79 | FAAH (0.37) | ALDH1A1TSHRUSP2HPGD | |
| SCHEMBL5369538 | 0.77 | ALDH1A1 (0.51) | ALDH1A1ALOX15TSHRFNTAFNTB | |
| SCHEMBL2028823 | 0.76 | ALOX15 (0.52) | ALDH1A1ALOX15TSHRKDM4EUSP2 | |
| SCHEMBL8863826 | 0.76 | ALDH1A1 (0.60) | ALDH1A1ALOX15TSHRFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204666-A1 | HEXAHYDROPYRROLO[1,2-C]PYRIMIDINES AS ANTIVIRAL, ANTIFUNGAL AND/OR ANTITUMOR AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001000626-A1 | HEXAHYDROPYRROLO[1,2-C]PYRIMIDINES AS ANTIVIRAL, ANTIFUNGAL AND/OR ANTITUMOR AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-01-04 | — | — | WO | disclosed |