Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 16/20 | 0.46 |
| ▸ | PDE4A | P27815 | 14/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 12/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | PDE5A | O76074 | 2/20 | 0.42 |
| ▸ | PDE1A | P54750 | 2/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.42 |
| ▸ | VEGFA | P15692 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14027108 | 0.92 | CASP1 (0.48) | CASP1HSD17B10PDE4BPDE4APDE4C | |
| SCHEMBL14027109 | 0.92 | CASP1 (0.47) | CASP1HSD17B10PDE4BPDE4APDE4C | |
| SCHEMBL6815488 | 0.89 | CASP1 (0.54) | CASP1HSD17B10PDE4BPDE4APDE4C | |
| SCHEMBL6826307 | 0.89 | CASP1 (0.54) | CASP1HSD17B10PDE4BPDE4APDE4C | |
| SCHEMBL5703639 | 0.85 | PDE4B (0.50) | CASP1HSD17B10PDE4BPDE4APDE4C | |
| SCHEMBL6826506 | 0.85 | CASP1 (0.50) | CASP1HSD17B10PDE4BPDE4APDE4C | |
| Carbromal SCHEMBL6229181 | 0.85 | CASP1 (0.41) | CASP1HSD17B10PDE4BPDE4APDE4C | |
| SCHEMBL5498111 | 0.84 | CASP1 (0.49) | CASP1HSD17B10PDE4BPDE4APDE4C | |
| SCHEMBL3167378 | 0.83 | CASP1 (0.47) | CASP1HSD17B10PDE4BPDE4APDE4C | |
| SCHEMBL7355456 | 0.82 | PDE4A (0.51) | PDE4BPDE4APDE4CPDE4DPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009735-B1 | METHOD FOR PRODUCING A 1-(3-CYCLOPENTENYLOXY- 4-ALKOXYPHENYL)-4- OXOCYCLOHEXANECARBONITRILE | LONZA AG (CH) | 2005-04-06 | — | — | EP | disclosed |
| EP-1009735-A1 | METHOD FOR PRODUCING A 1-(3-CYCLOPENTENYLOXY- 4-ALKOXYPHENYL)-4- OXOCYCLOHEXANECARBONITRILE | LONZA AG (CH) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999011607-A1 | METHOD FOR PRODUCING A 1-(3-CYCLOPENTENYLOXY- 4-ALKOXYPHENYL)-4- OXOCYCLOHEXANECARBONITRILE | LONZA AG (CH) | 1999-03-11 | — | — | WO | disclosed |