SCHEMBL6232636

SCHEMBL6232636

CCCCC1=C(C2CCCCC2C2=C(CCCC)[CH]c3cccc(-c4ccc(C(C)(C)C)cc4)c32)c2c(cccc2-c2ccc(C(C)(C)C)cc2)[CH]1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.30
CREBBP Q92793 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6231375 0.89 BRD4 (0.32) BRD4CREBBP
SCHEMBL7105422 0.77 NPC1 (0.35)
SCHEMBL7107950 0.73 NPC1 (0.33)
SCHEMBL28755362 0.73 TSHR (0.32) BRD4CREBBP
SCHEMBL5688730 0.73 PTAFR (0.31) BRD4CREBBP
SCHEMBL15668689 0.71 PTAFR (0.34) BRD4CREBBP
SCHEMBL7111654 0.70 NPC1 (0.36)
SCHEMBL5689802 0.70 TSHR (0.35) BRD4CREBBP
SCHEMBL5689679 0.70 PTAFR (0.32) BRD4CREBBP
SCHEMBL7103970 0.69 S1PR1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1313747-B1 METHOD FOR PRODUCING ALKYL-BRIDGED LIGAND SYSTEMS AND TRANSITION METAL COMPOUNDS BASELL POLYOLEFINE GMBH (DE) 2005-04-20 EP disclosed