Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | BRS3 | P32247 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231375 | 0.72 | BRD4 (0.32) | PTAFRCHRM3 | |
| SCHEMBL27816380 | 0.68 | PTGS2 (0.34) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6232855 | 0.68 | NPC1 (0.39) | KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL6232864 | 0.68 | BRD4 (0.32) | BRS3 | |
| SCHEMBL6229299 | 0.67 | NPC1 (0.36) | KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL7106833 | 0.67 | S1PR1 (0.39) | — | |
| SCHEMBL5689152 | 0.66 | EDNRB (0.35) | PTAFREDNRBEDNRAKDM4ENPC1 | |
| SCHEMBL6235387 | 0.65 | ABL1 (0.35) | NPC1RAB9A | |
| SCHEMBL21609920 | 0.64 | CYP3A4 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL27816378 | 0.63 | PTAFR (0.36) | PTAFRCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313747-B1 | METHOD FOR PRODUCING ALKYL-BRIDGED LIGAND SYSTEMS AND TRANSITION METAL COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |