Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6227192 | 0.80 | EGLN1 (0.41) | L3MBTL1HDAC1 | |
| SCHEMBL6226886 | 0.78 | NPC1 (0.51) | SMN1; SMN2KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL6353530 | 0.77 | NCF1 (0.42) | MGAMSMN1; SMN2KDM4EKDM4CKMT2A | |
| SCHEMBL6231884 | 0.76 | KDM4E (0.47) | SMN1; SMN2KDM4EKMT2AMEN1L3MBTL1 | |
| SCHEMBL5070882 | 0.76 | ALDH1A1 (0.51) | MGAMSMN1; SMN2KDM4EKDM4CKMT2A | |
| SCHEMBL4312684 | 0.73 | MGAM (0.56) | MGAMSMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL78691 | 0.72 | CA14 (0.41) | KDM4EKMT2AMEN1L3MBTL1GAA | |
| SCHEMBL3050230 | 0.71 | MEN1 (0.46) | SMN1; SMN2KDM4EKMT2AMEN1L3MBTL1 | |
| SCHEMBL2834319 | 0.71 | HDAC3 (0.55) | L3MBTL1ALDH1A1HDAC1 | |
| SCHEMBL7660084 | 0.71 | MGAM (0.53) | MGAMSMN1; SMN2KDM4EKMT2ACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1595866-A1 | COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV | Sanwa Kagaku Kenkyusho Co., Ltd. (JP) | 2005-11-16 | — | — | EP | disclosed |