SCHEMBL2834319

SCHEMBL2834319

CC(C)(C)OC(=O)N(CC(=O)O)Cc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.55
HDAC1 Q13547 1/20 0.55
HDAC2 Q92769 1/20 0.55
NCOR2 Q9Y618 1/20 0.55
CTSS P25774 3/20 0.52
CTSL P07711 2/20 0.52
CTSB P07858 2/20 0.52
AKT1 P31749 3/20 0.48
LMNA P02545 1/20 0.46
RECQL P46063 1/20 0.46
ALDH1A1 P00352 1/20 0.44
BACE1 P56817 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CTSK P43235 1/20 0.42
RIPK1 Q13546 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12894955 0.91 HDAC3 (0.51) HDAC3HDAC1HDAC2NCOR2CTSS
SCHEMBL13021076 0.91 CTSL (0.54) HDAC3HDAC1HDAC2NCOR2CTSS
SCHEMBL2897902 0.87 HDAC3 (0.46) HDAC3HDAC1HDAC2NCOR2CTSS
SCHEMBL3858652 0.87 HDAC3 (0.46) HDAC3HDAC1HDAC2NCOR2CTSS
SCHEMBL13021069 0.87 CTSL (0.50) HDAC3HDAC1HDAC2NCOR2CTSS
SCHEMBL13021079 0.87 CTSL (0.50) HDAC3HDAC1HDAC2NCOR2CTSS
SCHEMBL7594665 0.86 HDAC3 (0.44) HDAC3HDAC1HDAC2NCOR2CTSS
SCHEMBL23288368 0.86 LMNA (0.60) HDAC3HDAC1HDAC2NCOR2CTSS
SCHEMBL13021085 0.86 CTSL (0.49) HDAC3HDAC1HDAC2NCOR2CTSS
SCHEMBL4278729 0.85 HDAC3 (0.54) HDAC3HDAC1HDAC2NCOR2CTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698170-A1 GLYCINAMIDE DERIVATIVES FOR USE IN THE TREATMENT OF SALMONELLOSIS Eberhard-Karls-Universität Tübingen (DE) 2026-02-25 EP disclosed
WO-2025202493-A1 ANTIMICROBIAL PEPTOID TERPOLYMERS, PREPARATIONS AND USES THEREOF VIKYNG AI (FR) 2025-10-02 WO disclosed
WO-2025088200-A2 ACID PHOSPHATASE 3 LIGANDS FOR TARGETED DELIVERY APPLICATIONS PHILOCHEM AG (CH) 2025-05-01 WO disclosed
WO-2024218333-A1 GLYCINAMIDE DERIVATIVES FOR USE IN THE TREATMENT OF SALMONELLOSIS EBERHARD KARLS UNIVERSITÄT TÜBINGEN MEDIZINISCHE FAKULTÄT (DE) 2024-10-24 WO disclosed
US-20240189486-A1 ANTIMICROBIAL CATIONIC PEPTOID AND N-SUBTITUTED PEPTIDIC COPOLYMERS, PREPARATION AND USES THEREOF UNIVERSITÉ DE BORDEAUX (FR) 2024-06-13 US disclosed
EP-4294821-A1 ANTIMICROBIAL CATIONIC PEPTOID AND N-SUBTITUTED PEPTIDIC COPOLYMERS, PREPARATION AND USES THEREOF UNIVERSITE DE BORDEAUX (FR) 2023-12-27 EP disclosed
CN-115368261-A Synthesis method of N-allyl-N-benzyl-2- (benzylamino) acetamide 武汉理工大学 2022-11-22 CN disclosed
WO-2022175319-A1 ANTIMICROBIAL CATIONIC PEPTOID AND N-SUBTITUTED PEPTIDIC COPOLYMERS, PREPARATION AND USES THEREOF Universite de Bordeaux (FR) 2022-08-25 WO disclosed
EP-4047012-A1 ANTIMICROBIAL CATIONIC PEPTOID AND N-SUBTITUTED PEPTIDIC COPOLYMERS, PREPARATION AND USES THEREOF Université de Bordeaux (FR) 2022-08-24 EP disclosed
US-11389464-B2 Arginase inhibitors as therapeutics MARS, INCORPORATED (US) 2022-07-19 US disclosed
EP-0970075-A1 PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY ZAMBON GROUP S.p.A. (IT) 2000-01-12 EP disclosed
EP-0783318-A4 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO INC (US) 1999-10-20 EP disclosed
EP-0871619-A1 PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) 1998-10-21 EP disclosed
WO-1998043972-A1 PYRIMIDINONE-1,3-OXATHIOLANE DERIVATIVES WITH ANTIVIRAL ACTIVITY ZAMBON GROUP S.P.A. (IT) 1998-10-08 WO disclosed
US-5700779-A ALLEVIATING PAIN, ASTHMA, INFLAMMATION, CEREBRAL EDEMA, CARDIOVASCULAR DYSFUNCTION CORTECH, INC. (US) 1997-12-23 US disclosed
EP-0783318-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO. INC. (US) 1997-07-16 EP disclosed
WO-1997024343-A1 PHENYL THIAZOLE DERIVATIVES WITH ANTI HERPES VIRUS PROPERTIES BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 1997-07-10 WO disclosed
US-5585359-A LACK OF THIOL MOIETY PREVENTS THIOL-DEPENDENT CHEMICAL REACTIONS AND REDUCES SYSTEMIC TOXICITY MERCK & CO., INC. (US) 1996-12-17 US disclosed
US-5527882-A BRADYKININ THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-06-18 US disclosed
WO-1996009836-A1 INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 1996-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11389464-B2 Arginase inhibitors as therapeutics ARG1, ARG2, PRMT1 HDAC3 324/4885HDAC1 108/4885HDAC2 101/4885
US-20240189486-A1 ANTIMICROBIAL CATIONIC PEPTOID AND N-SUBTITUTED PEPTIDIC COPOLYMERS, PREPARATION AND USES THEREOF NGLY1, VIP, FPR3 HDAC3 4231/4885HDAC1 4563/4885HDAC2 4296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.