Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.48 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.48 |
| ▸ | CLK2 | P49760 | 2/20 | 0.48 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.48 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.48 |
| ▸ | MARK3 | P27448 | 1/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6233612 | 0.84 | IRAK4 (0.48) | KMT2AIRAK4MEN1MAP4K4CSNK1D | |
| SCHEMBL24900462 | 0.82 | MAPT (0.55) | KMT2AIRAK4MEN1RAB9AGAA | |
| SCHEMBL622609 | 0.78 | CFTR (0.50) | KMT2AIRAK4MEN1RAB9AGAA | |
| SCHEMBL6231431 | 0.78 | KDM4E (0.43) | KMT2AMEN1RAB9AGAAL3MBTL1 | |
| SCHEMBL588563 | 0.78 | RAB9A (0.62) | KMT2AMEN1RAB9AALDH1A1PKM | |
| SCHEMBL28987743 | 0.77 | MEN1 (0.71) | KMT2AMEN1RAB9AGAAL3MBTL1 | |
| SCHEMBL31441369 | 0.77 | MEN1 (0.71) | KMT2AMEN1RAB9AGAAL3MBTL1 | |
| SCHEMBL8339799 | 0.77 | KMT2A (0.57) | KMT2AIRAK4RAB9ARPS6KA5TDP1 | |
| SCHEMBL11195213 | 0.77 | KMT2A (0.83) | KMT2ARAB9ATDP1TSHRALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL20358007 | 0.76 | RAB9A (0.60) | KMT2AMEN1RAB9AALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004092181-A9 | HETEROCYCLIC MCHR1 ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2005-01-27 | — | — | WO | disclosed |